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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3209 | AMG-337 | AMG337 | c-Met/HGFR |
AMG-337 is an effective and highly specific ATP-competitive MET kinase inhibitor. In enzymatic assays, AMG-337(AMG337) inhibits MET kinase activity (IC50: < 5 nM). | |||
T8317 | 5'-Fluoroindirubinoxime | 5'-FIO | FLT |
5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM). | |||
T8825 | Capmatinib 2HCl.H2O | INCB28060 2HCl.H2O,INC-280 2HCl.H2O,NVP-INC280 2HCl.H2O | c-Met/HGFR |
Capmatinib 2HCl.H2O (NVP-INC280 2HCl.H2O) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity. | |||
T8416 | Capmatinib xHCl | INCB28060,Capmatinib hydrochloride(free base),INC280 | c-Met/HGFR |
Capmatinib xHCl (INCB28060) is a potent, orally active, selective, and ATP competitive c-Met kinase inhibitor, potently blocking in vitro kinase activity (IC50 = 0.13 nM) as well as constitutive or HGF-stimulated activit... | |||
T1963 | Capmatinib | NVP-INC280,INC-280,INCB28060 | Apoptosis , c-Met/HGFR |
Capmatinib (INCB28060) is an orally bioavailable inhibitor of the proto-oncogene c-Met (HGFR)with potential antineoplastic activity. | |||
T9078 | LY3405105 | 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester | CDK |
LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester) is a novel CDK7 inhibitors. | |||
T4260 | Capmatinib 2HCl | INC-280 2HCl,INCB28060 2HCl | c-Met/HGFR |
Capmatinib 2HCl (INC-280 2HCl) is a novel, ATP-competitive inhibitor of c-MET kinase with an IC50 with 0.13 nM.Capmatinib 2HCl exhibits picomolar enzymatic potency and is highly specific for c-MET with more than 10, 000-... | |||
T8296 | 5,7,4'-Trimethoxyflavone | 4',5,7-Trimethoxyflavone | Apoptosis , PARP , Caspase |
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand. |