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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8462 | Enoximone | PDE | |
Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure. | |||
T27475 | GSK356278 | GSK-356278,GSK 356278 | PDE |
GSK356278 is an effective and selective inhibitor of phosphodiesterase 4 (PDE4), with pIC50s of 8.6, 8.8, and 8.7 for human PDE4A, PDE4B, and PDE4D, respectively. GSK356278 has anti-inflammatory, anxiolytic, and cognitio... | |||
T5496 | ML-030 | PDE | |
ML-030 is a potent and selective inhibitor of PDE4(PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2 with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM, respectively) | |||
T6644 | Rolipram | SB 95952,ZK 62711,(R,S)-Rolipram | HIV Protease , Antibacterial , PDE |
Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties. | |||
T61794 | LASSBio-1632 | ||
LASSBio-1632 is a novel anti-asthmatic lead candidate that selectively inhibits PDE4A and PDE4D isoenzymes, leading to the suppression of airway hyper-reactivity (AHR) and TNF-α production in lung tissue. With high exper... | |||
T38002 | LEO 39652 | ||
LEO 39652, a dual-soft PDE4 inhibitor, demonstrates potent inhibition of PDE4 subtypes A, B, C, and D with respective IC50 values of 1.2 nM, 1.2 nM, 3.0 nM, and 3.8 nM. Additionally, it inhibits TNF-α with an IC50 of 6.0... | |||
T33947 | PF-06445974 | PF-6445974,PF6445974,PF06445974,PF 6445974 | |
PF-06445974 has good selectivity for PDE4D, excellent brain permeability, and has a high level of specific binding in the "cold tracer" study. |