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Search Results for " pde4a "

7

Compounds

Cat No. Product Name Synonyms Targets
T8462 Enoximone PDE
Enoximone is a selective inhibitor of phosphodiesterase III (PDE3), with treatment of congestive heart failure.
T27475 GSK356278 GSK-356278,GSK 356278 PDE
GSK356278 is an effective and selective inhibitor of phosphodiesterase 4 (PDE4), with pIC50s of 8.6, 8.8, and 8.7 for human PDE4A, PDE4B, and PDE4D, respectively. GSK356278 has anti-inflammatory, anxiolytic, and cognitio...
T5496 ML-030 PDE
ML-030 is a potent and selective inhibitor of PDE4(PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2 with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM, respectively)
T6644 Rolipram SB 95952,ZK 62711,(R,S)-Rolipram HIV Protease , Antibacterial , PDE
Rolipram (SB 95952) is a phosphodiesterase 4 inhibitor with antidepressant properties.
T61794 LASSBio-1632
LASSBio-1632 is a novel anti-asthmatic lead candidate that selectively inhibits PDE4A and PDE4D isoenzymes, leading to the suppression of airway hyper-reactivity (AHR) and TNF-α production in lung tissue. With high exper...
T38002 LEO 39652
LEO 39652, a dual-soft PDE4 inhibitor, demonstrates potent inhibition of PDE4 subtypes A, B, C, and D with respective IC50 values of 1.2 nM, 1.2 nM, 3.0 nM, and 3.8 nM. Additionally, it inhibits TNF-α with an IC50 of 6.0...
T33947 PF-06445974 PF-6445974,PF6445974,PF06445974,PF 6445974
PF-06445974 has good selectivity for PDE4D, excellent brain permeability, and has a high level of specific binding in the "cold tracer" study.
TargetMol