bradycardia — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8441	Lerisetron		5-HT Receptor
	Lerisetron is an antagonist of serotonin type 3 (5-HT3) receptor, with antiemetic activity.		5-HT Receptor
T7421	Melperone		Others
	Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.		Others
T13370	YM-46303		AChR
	YM-46303 is a selective and potent muscarinic receptor antagonist that exhibits high affinity for the M3 receptor.YM-46303 can be used to study bradycardia in medullary rats.		AChR
TP1898	HS024	HS 024	Melanocortin Receptor
	HS024 is a highly potent melanocortin MC4 receptor antagonist (Ki values are 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors respectively). Increases food intake, and blocks α-MSH- and MTII-...		Melanocortin Receptor
T27607	Indisetron Dihydrochloride	N3389T,Sinseron,N-3389T,N 3389T
	Indisetron Dihydrochloride is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia.
T38443	Methoctramine tetrahydrochloride
	Methoctramine tetrahydrochloride is a potent and cardioselective antagonist of the M2 muscarinic receptor, capable of inhibiting Muscarine-induced bradycardia in vivo.
T70729	Indisetron
	Indisetron is a 5-HT(3) and 5-HT(4) receptor antagonist. Indisetron reduces 2-methyl-5-serotonin (HT)-induced bradycardia.
T21411	Isoproterenol	Norisodrine,Isoprenaline,Novodrin,Isuprel,Medihaler-Iso	Endogenous Metabolite , Adrenergic Receptor
	Isoproterenol (Norisodrine) is a non-selective and orally active β-adrenoceptor agonist.Isoproterenol is a potent peripheral vasodilator and bronchodilator.Isoproterenol can be used in the study of bradycardia and bronch...		Endogenous Metabolite , Adrenergic Receptor
T10913	Cyclobuxine D		Others
	Cyclobuxine D is a steroidal alkaloid extracted from Buxus microphylla. Cyclostatin D has obvious bradycardia effect on rat heart, and inhibits acetylcholine and Ba ++ induced longitudinal muscle contraction isolated fro...		Others
T68263	MDL-72567
	MDL-72567 is a dihydropyridine calcium antagonist that causes vasodilation and direct sinus bradycardia.
T31119	CVT-2759	UNII-42E8N8RC9Z,CVT2759
	CVT-2759 is A potential partial agonist for A(1)-ADORs, and it may be useful to slow atrioventricular node conduction to reduce ventricular rate without causing the atrioventricular block, bradycardia, atrial arrhythmias...
T2S1727	Lycorenine		Antifection
	Lycorenine may produce a decrease in blood pressure as the result of alpha-adrenergic blockade in conjunction with the reduction of the spontaneous sympathetic nerve activity, and produce bradycardia by modifying vagal a...		Antifection
T70421	VCP746
	VCP-746 is a potent adenosine A2B receptor agonist that stimulates anti-fibrotic signalling. VCP746 reduces hypertrophy in a rat neonatal cardiac myocyte model. VCP746 is a hybrid molecule consisting of an adenosine moie...
T26770	Bencycloquidium Bromide	BCQB
	Bencycloquidium Bromide is a muscarinic M3 antagonist. Bencycloquidium bromide inhibits nasal hypersecretion in a rat model of allergic rhinitis. Bencycloquidium Bromide showed high affinity toward the M(3) receptor in C...
T31194	Dalapon	Basfapon B,Dowpon M,Dawpon-Rae
	Dalapon is a selective herbicide used to control perennial grasses. The major use of dalapon is on food crops including sugarcane and sugar beets. Its use is no longer authorized in France. The National Institute for Occ...
T37728	Methoctramine (hydrate)
	Methoctramine is a selective antagonist of M2 muscarinic acetylcholine receptors (IC50 = 6.1 nM in CHO-K1 cell membranes).[1] It is selective for M2 over M1, M3, M4, and M5 receptors (IC50s = 92, 770, 260, and 217 nM, re...