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Search Results for " ata "

20

Compounds

Cat No. Product Name Synonyms Targets
T8333 Aurintricarboxylic acid ATA,NSC-4056,NSC4056,NSC 4056 Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme.
T19572 T4-ATA (S-isomer) Others
T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA.
T19571 T3-ATA (S-isomer) Others
T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone.
T71030 3-ATA
3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons.
T71028 Lisinopril, epsilon-biotinamidocaproyl-
Lisinopril, epsilon-biotinamidocaproyl- is an angiotensin converting enzyme (ACE) inhibitor.
T15259 Evatanepag CP-533536 free acid Prostaglandin Receptor
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l...
T6252 Ipatasertib GDC-0068,RG7440 Akt
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively.
T15374 Ipatasertib dihydrochloride GDC-0068 dihydrochloride,RG-7440 dihydrochloride Akt , PKA
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively).
T9567 Samatasvir ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719 HCV Protease
Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A.
T77122 Praluzatamab Others
Praluzatamab is a monoclonal antibody targeting an activated white blood cell adhesion molecule (ALCAM/CD116). Praluzatamab is a naked antibody to Praluzatamab ravtansine and can be used to synthesize antibody active mol...
T76674 Cibisatamab Others
Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of ...
T0236 Azatadine dimaleate SCH10649,Azatadine Maleate 5-HT Receptor , AChR , Histamine Receptor
Azatadine dimaleate (SCH10649) is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM).
TN7047 6-O-Methylcatalpol Others
6-O-Methylcatalpol is a natural product that is isolated from the roots of S. ningpoensis.
T24932 Vatanidipine AE-0047,AE 0047,AE0047 Calcium Channel
Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting hypotensive action was observed in various experimental hypertensi...
T78835 Phosphatase-IN-1 Antifungal
Phosphatase-IN-1 (compound II-8), a propranolol derivative, acts as an inhibitor of phosphatidate phosphatase (Pah). It binds to MoPah1 with an affinity constant of 19.8 μM, demonstrating growth inhibition of plant patho...
T15719 Latanoprostene bunod LBN,NCX116 Others
Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o...
T9840 Ataquimas Immunology/Inflammation related
Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells.
T2520 Desloratadine Sch34117,NSC 675447 Endogenous Metabolite , Histamine Receptor
Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot...
T23631 Adatanserin WY-50324,WY 50324,WAY SEB 324,WY50324 5-HT Receptor
Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist with potential neuroprotective activity for the study of coke oven and depression.
T6229 Daclatasvir Daklinza,EBP 883,BMS-790052 HCV Protease
Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.
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