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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8333 | Aurintricarboxylic acid | ATA,NSC-4056,NSC4056,NSC 4056 | Apoptosis , P2X Receptor , Influenza Virus , Topoisomerase |
Aurintricarboxylic acid (NSC-4056) is a strong inhibitor of topoisomerases and other nucleases. It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. | |||
T19572 | T4-ATA (S-isomer) | Others | |
T4-ATA S-isomer, the active form of the thyroid hormone, represents the S-isomer of T4-ATA. | |||
T19571 | T3-ATA (S-isomer) | Others | |
T3-ATA S-isomer, the S-isomer of T3-ATA, represents the active form of the thyroid hormone. | |||
T71030 | 3-ATA | ||
3-ATA is a selective cyclin-dependent kinase 4 (Cdk4) inhibitor, attenuating kainic acid-induced apoptosis in neurons. | |||
T71028 | Lisinopril, epsilon-biotinamidocaproyl- | ||
Lisinopril, epsilon-biotinamidocaproyl- is an angiotensin converting enzyme (ACE) inhibitor. | |||
T15259 | Evatanepag | CP-533536 free acid | Prostaglandin Receptor |
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l... | |||
T6252 | Ipatasertib | GDC-0068,RG7440 | Akt |
Ipatasertib (GDC-0068) (GDC-0068), a highly specific pan-Akt inhibitor, targets Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM, respectively. | |||
T15374 | Ipatasertib dihydrochloride | GDC-0068 dihydrochloride,RG-7440 dihydrochloride | Akt , PKA |
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive inhibitor of pan-Akt (IC50s: 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively). | |||
T9567 | Samatasvir | ATOLIHZIXHZSBA-BTSKBWHGSA-N,IDX719 | HCV Protease |
Samatasvir (ATOLIHZIXHZSBA-BTSKBWHGSA-N) is a pan-genotypic inhibitor of the HCV non-structural protein 5A. | |||
T77122 | Praluzatamab | Others | |
Praluzatamab is a monoclonal antibody targeting an activated white blood cell adhesion molecule (ALCAM/CD116). Praluzatamab is a naked antibody to Praluzatamab ravtansine and can be used to synthesize antibody active mol... | |||
T76674 | Cibisatamab | Others | |
Cibisatamab is a T-cell bispecific antibody that acts as a T-cell splicer.Cibisatamab targets carcinoembryonic antigen (CEA) on cancer cells and CD3 on T-cells, and triggers T-cell killing when the CEA on the surface of ... | |||
T0236 | Azatadine dimaleate | SCH10649,Azatadine Maleate | 5-HT Receptor , AChR , Histamine Receptor |
Azatadine dimaleate (SCH10649) is an inhibitor for histamine(IC50=6.5 nM) and cholinergic(IC50=10 nM). | |||
TN7047 | 6-O-Methylcatalpol | Others | |
6-O-Methylcatalpol is a natural product that is isolated from the roots of S. ningpoensis. | |||
T24932 | Vatanidipine | AE-0047,AE 0047,AE0047 | Calcium Channel |
Vatanidipine (AE0047) is a novel dihydropyridine (DHP)-type calcium channel blocker with slow-onset pharmacological actions.A slow-onset and long-lasting hypotensive action was observed in various experimental hypertensi... | |||
T78835 | Phosphatase-IN-1 | Antifungal | |
Phosphatase-IN-1 (compound II-8), a propranolol derivative, acts as an inhibitor of phosphatidate phosphatase (Pah). It binds to MoPah1 with an affinity constant of 19.8 μM, demonstrating growth inhibition of plant patho... | |||
T15719 | Latanoprostene bunod | LBN,NCX116 | Others |
Latanoprostene bunod (LBN) is nitric oxide (NO)-donating prostaglandin F2a analog and is a topical ophthalmic therapeutic. It is used for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma o... | |||
T9840 | Ataquimas | Immunology/Inflammation related | |
Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells. | |||
T2520 | Desloratadine | Sch34117,NSC 675447 | Endogenous Metabolite , Histamine Receptor |
Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot... | |||
T23631 | Adatanserin | WY-50324,WY 50324,WAY SEB 324,WY50324 | 5-HT Receptor |
Adatanserin (WY 50324) is a mixed 5-HT1A receptor partial agonist and a 5-HT2A and 5-HT2C receptor antagonist with potential neuroprotective activity for the study of coke oven and depression. | |||
T6229 | Daclatasvir | Daklinza,EBP 883,BMS-790052 | HCV Protease |
Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3. |