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Tris(3-hydroxypropyltriazolylmethyl)amine
TXB-00017760952-88-3
Tris(3-hydroxypropyltriazolylmethyl)amine (THPTA) serves as an accelerating ligand in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAC), shielding cells from oxidative damage caused by reactive oxygen species generated by copper-catalyzed ascorbate reduction. In addition, Tris(3-hydroxypropyltriazolylmethyl)amine protects the histidine components of biomolecules in a manner proportional to the ligand concentration.
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