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5'-chloro-5'-deoxyadenosine

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  • Inhibitors & Agonists
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5'-chloro-5'-Deoxyadenosine (hydrate)
T36869698999-09-6
5'-chloro-5'-Deoxyadenosine (hydrate) is a nucleoside analog used as a substrate in polyketide biosynthesis. S-(5'-adenosyl)-L-methionine can be converted to 5'-chloro-5'-deoxyadenosine in a reaction catalyzed by a SAM-dependent chlorinase. Through a 7-step route, 5'-chloro-5'-deoxyadenosine can be converted to chloroethylmalonyl-CoA, which has been shown to be involved in the biosynthesis of the anticancer agent salinosporamide A in the marine bacterium S. tropica.
  • $246
35 days
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N6-Benzoyl-2'-chloro-5'-O-(4,4'-dimethoxytrityl)-2'-deoxyadenosine
TNU10852243079-24-3
Nucleoside Derivatives - Halo-nucleoside; 2'-Modified nucleoside, Protected nucleosides with NH2/OH open
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7-10 days
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