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Results for "

2aemp tfa

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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2-AEMP TFA
2AEMP,2-AEMP,2 AEMP
T26380321882-95-5
2-AEMP TFA is a potent and rapidly acting antagonist of GABA(A)-ρ1 receptors. 2-AEMP is an analog of GABA.
    Inquiry
    Oxaliplatin
    L-OHP
    T016461825-94-3
    Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autophagy.
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    TargetMol | Inhibitor Hot
    Gemcitabine
    NSC 613327, LY188011
    T025195058-81-4
    Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.
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    Cyclosporin A
    Cyclosporine A, Cyclosporine, Ciclosporin
    T094559865-13-3
    Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM).
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    Decitabine
    NSC 127716, Dacogen, 5-Aza-CdR, 5-Aza-2'-deoxycytidine
    T15082353-33-5
    Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.
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    Erastin
    T1765571203-78-6
    Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations.
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    TargetMol | Inhibitor Hot
    Ruxolitinib
    INCB018424, (R)-Ruxolitinib
    T1829941678-49-5
    Ruxolitinib (INCB018424) is a JAK1 2 inhibitor (IC50=3.3 2.8 nM) that is potent and selective. Rixolitinib exhibits antitumor activity and induces autophagy and apoptosis.
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    TargetMol | Inhibitor Hot
    (-)-Epigallocatechin Gallate
    Epigallocatechol Gallate, EGCG
    T2988989-51-5
    (-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells.
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    Staurosporine
    CGP 41251, Antibiotic AM-2282, AM-2282
    T668062996-74-1
    Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6 15 2 3 3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.
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    TargetMol | Inhibitor Hot
    BI-2493
    T720612937344-16-4In house
    BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.
    • Inquiry Price
    8-10weeks
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    TargetMol | Inhibitor Hot
    RMC-6236
    RMC6236
    T746982765081-21-6
    RMC-6236 is an orally effective and novel triple complex RAS (ON) MULTI inhibitor, which is a potent non covalent inhibitor of multiple RAS variants in GTP binding state. RMC-6236 has anti-tumor activity and can be used in research related to RAS driven tumors. With rich experience in compound synthesis, we can provide fast customized synthesis services for this product according to your research needs.
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    TargetMol | Inhibitor Hot
    MRTX1133
    T93032621928-55-8In house
    MRTX1133 is a KRAS G12D inhibitor (KD=0.2 pM) that is potent, selective, and non-covalent. MRTX1133 exhibits inhibitory activity against KRAS G12D-mutated tumors, but not against KRAS wild-type tumors.
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    TargetMol | Inhibitor Hot
    Pioglitazone
    U 72107
    T0214111025-46-8
    Pioglitazone (U 72107) is an insulin sensitizing agent and thiazolidinedione indicated for the treatment of type 2 diabetes, and has been linked to rare instances of acute liver injury.
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    TargetMol | Inhibitor Hot
    Rutin
    Rutoside, Quercetin 3-O-rutinoside
    T0795153-18-4
    Rutin (Quercetin 3-O-rutinoside), a flavonoid, has a variety of biological activities including antiallergic, anti-inflammatory, antiproliferative, and anticarcinogenic properties.
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    TargetMol | Inhibitor Hot
    Acetylcysteine
    N-Acetyl-L-cysteine, N-Acetylcysteine, N-Acetyl Cysteine, NAC, LNAC
    T0875616-91-1
    Acetylcysteine (NAC) is an N-acetyl derivative of cysteine, a ROS inhibitor and mucolytic agent. Acetylcysteine induces apoptosis, can be used to reduce mucus thickness, and has anti-influenza viral activity.
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    TargetMol | Inhibitor Hot
    Corticosterone
    Kendall's compound B, Corticosterone (From plants), 17-Deoxycortisol, 11β,21-Dihydroxyprogesterone
    T0948L50-22-6
    Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stress responses in the body.
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    TargetMol | Inhibitor Hot
    Paclitaxel
    Taxol, NSC 125973
    T096833069-62-4
    Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
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    TargetMol | Inhibitor Hot
    TargetMol
    2',3'-cGAMP sodium
    2'-3'-cyclic GMP-AMP sodium
    T10065L2734858-36-5In house
    2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) is a second messenger in cellular innate immunity, catalyzed by cGAMP synthase (cGAS) under DNA binding conditions. It binds to STING to form a dimer, inducing the production and expression of interferon-β and other cytokines.
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    TargetMol | Inhibitor Hot
    5-HT1A modulator 1
    5-HT1Amodulator1
    T10168142477-34-7In house
    5-HT1A modulator 1 exhibits high affinities for the 5-HT1A, α1-adrenergic receptor, and D2 receptor (IC50s = 2 nM, 10 nM, and 40 nM).
    • Inquiry Price
    6-8 weeks
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    TargetMol | Inhibitor Hot
    akt kinase inhibitor
    T10276842148-40-7In house
    AKT Kinase Inhibitor is an Akt inhibitor with antitumor activity that selectively inhibits cell proliferation in a dose-dependent manner.
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    10-14 weeks
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    TargetMol | Inhibitor Hot
    Capsaicin
    Zostrix, Qutenza, 8-Methyl-N-vanillyl-trans-6-nonenamide, (E)-Capsaicin
    T1062404-86-4
    Capsaicin ((E)-Capsaicin) is a natural product extracted from Capsicum annuum, and is a TRPV1 agonist (EC50=0.29 μM). Capsaicin has antitumor, anti-inflammatory, antioxidant and neuroprotective activities.
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    TargetMol | Inhibitor Hot
    Dexamethasone
    Prednisolone F, NSC 34521, MK 125, Hexadecadrol
    T107650-02-2
    Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.
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    TargetMol | Inhibitor Hot
    LTB4-IN-1
    Anti-inflammatory agent 2
    T10917133012-00-7In house
    LTB4-IN-1 (Anti-inflammatory agent 2) with IC50 of 70 nM is an inhibitor of leukotriene synthesis (LTB4).
    • Inquiry Price
    6-8 weeks
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    TargetMol | Inhibitor Hot
    Durlobactam sodium salt
    ETX2514 sodium salt
    T111251467157-21-6
    Durlobactam sodium salt (ETX2514) is a beta-lactamase inhibitor with IC50 values of 4 nM, 14 nM and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.
    • Inquiry Price
    14-16 weeks
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    TargetMol | Inhibitor Hot