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Search Results for " 2-amino-5-methyl-3-thiophenecarbonitrile "

1

Compounds

360

Recombinant Proteins

Cat No. Product Name
T1376 2-Amino-5-methyl-3-thiophenecarbonitrile COX
2-Amino-5-methyl-3-thiophenecarbonitrile is an organic compund with molecular fomula C6H6N2S.
Cat No. Product Name Species Source
TMPY-05308 CD45 Protein, Human, Recombinant (aa 1-529, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-05191 CD47 Protein, Human, Recombinant, Biotinylated Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b...
TMPY-00892 Neuropilin-2 Protein, Human, Recombinant (His) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classⅢ semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellul...
TMPY-04683 CD47 Protein, Human, Recombinant Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b...
TMPY-01020 Periostin Protein, Human, Recombinant (His) Human HEK293
Periostin ( POSTN ), also known as OSF2 (osteoblast specific factor 2), is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesion and movement, as well as collagen fibrillogenesis. Postn is expressed in unique growth centers during embryonic development where it facilitates epithelial-mesenchymal transition (EMT) of select cell populations undergoing reorganization. In the adult, Postn expression is specifically induced ...
TMPY-03763 Neuropilin-2 Protein, Human, Recombinant (hFc) Human HEK293
Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation factor V/VIII homology domains, and a MAM (meprin, tyrosine phosphatase domain) region. NRP-2 is a receptor capable of binding two disparate ligands, classⅢ semaphorins (SEMA) and vascular endothelial growth factors (VEGF), and thus regulates two diverse systems by activating cellul...
TMPY-01897 PRSS3 Protein, Human, Recombinant (His) Human HEK293
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPY-01180 CD86 Protein, Human, Recombinant (His) Human HEK293
CD86, also known as B-lymphocyte activation antigen B7-2 (referred to as B70), is a member of the cell surface immunoglobulin superfamily. B7-2 exists predominantly as a monomer on cell surfaces and interacts with two co-stimulatory receptors CD28 and cytotoxic T lymphocyte-associated antigen 4 (CTLA-4) expressed on T cells, and thus induces the signal pathways which regulate T cell activation and tolerance, cytokine production, and the generation of CTL. It is indicated that contacts between B ...
TMPY-04298 CDCP1 Protein, Human, Recombinant (His) Human HEK293
CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, CDH3/P-cadherin, SDC1/syndecan-1, SDC4/syndecan-4 and the serine protease ST14/MT-SP1. It also interacts with SRC and PRKCG/protein kinase C gamma. CDCP1 is taken as a key regulator of EGF/EGFR-induced cell migration. It has been shown that signaling via EGF/EGFR induces migratio...
TMPY-00072 GITR Protein, Human, Recombinant (His) Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-00480 NCAM Protein, Human, Recombinant (His) Human HEK293
NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. NCAM1 is involved in neuron-neuron adhesion, neurite fasciculation, the outgrowth of neurites, etc. It has also been shown to be...
TMPY-04935 CD47 Protein, Human, Recombinant (aa 1-139, His) Human HEK293
CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain and is a receptor for the C-terminal cell binding domain of thrombospondin. It may play a role in membrane transport and signal transduction. CD47 is also a membrane protein, which is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. It is very broadly distributed on normal adult tissues, as well as ovarian tumors, being especially abundant in some epithelia and the b...
TMPY-04142 RANK/TNFRSF11A Protein, Human, Recombinant (hFc) Human HEK293
TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland. It is an essential mediator for osteoclast and lymph node development. TNFRSF11A and its ligand are important regulators of the interaction between T cells and dendritic cells. It can interact with various TRAF family proteins, through which this recep...
TMPY-05748 CD45 Protein, Human, Recombinant (aa 26-577, His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-00132 Mesothelin Protein, Human, Recombinant Human HEK293
The megakaryocyte potentiating factor belongs to the mesothelin family. This family is comprised of several mammalian pre-pro-megakaryocyte potentiating factor precursor (MPF) or mesothelin proteins. Mesothelin is a glycosylphosphatidylinositol-linked glycoprotein highly expressed in mesothelial cells, mesotheliomas, and ovarian cancer, but the biological function of the protein is not known. Megakaryocyte potentiating factor is highly expressed in mesotheliomas, ovarian cancers, and some squamo...
TMPY-02011 CD96 Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins d...
TMPY-00748 Nectin-2 Protein, Human, Recombinant Human HEK293
Cluster of Differentiation 112 (CD112), also known as poliovirus receptor related protein 2 (PVRL2 or PRR2), is a single-pass type I transmembrane glycoprotein belonging to the Immunoglobulin superfamily. CD112 protein also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and thus is involved in cell to cell spreading of these viruses. CD112 protein has been identified as the ligand for DNAM-1 (CD226), and the interaction of CD226/CD112 protein can in...
TMPY-00850 ST2/IL-1 RL1 Protein, Human, Recombinant Human HEK293
IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in fa...
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His) Human HEK293
FGFR3, also known as CD333, is a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. FGFRs are transmembrane catalytic receptors that have intracellular tyrosine kinase activity. Mutations in FGFR genes are the cause of several human developmental disorders characterized by skeletal abnormalitie...
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His) Human HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted protein which belongs to the clusterin family. Clusterin/Apolipoprotein J/Apo-J is an enigmatic glycoprotein with a nearly ubiquitous tissue distribution and an apparent involvement in biological processes ranging from mammary gland involution to neurodegeneration in Alzheimer's dise...

Recombinant Proteins

CD45 Protein, Human, Recombinant (aa 1-529, His)
TMPY-05308
Species: Human
Source: HEK293
CD47 Protein, Human, Recombinant, Biotinylated
TMPY-05191
Species: Human
Source: HEK293
Neuropilin-2 Protein, Human, Recombinant (His)
TMPY-00892
Species: Human
Source: HEK293
CD47 Protein, Human, Recombinant
TMPY-04683
Species: Human
Source: HEK293
Periostin Protein, Human, Recombinant (His)
TMPY-01020
Species: Human
Source: HEK293
Neuropilin-2 Protein, Human, Recombinant (hFc)
TMPY-03763
Species: Human
Source: HEK293
PRSS3 Protein, Human, Recombinant (His)
TMPY-01897
Species: Human
Source: HEK293
CD86 Protein, Human, Recombinant (His)
TMPY-01180
Species: Human
Source: HEK293
CDCP1 Protein, Human, Recombinant (His)
TMPY-04298
Species: Human
Source: HEK293
GITR Protein, Human, Recombinant (His)
TMPY-00072
Species: Human
Source: HEK293
NCAM Protein, Human, Recombinant (His)
TMPY-00480
Species: Human
Source: HEK293
CD47 Protein, Human, Recombinant (aa 1-139, His)
TMPY-04935
Species: Human
Source: HEK293
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
TMPY-04142
Species: Human
Source: HEK293
CD45 Protein, Human, Recombinant (aa 26-577, His)
TMPY-05748
Species: Human
Source: HEK293
Mesothelin Protein, Human, Recombinant
TMPY-00132
Species: Human
Source: HEK293
CD96 Protein, Human, Recombinant (His)
TMPY-02011
Species: Human
Source: HEK293
Nectin-2 Protein, Human, Recombinant
TMPY-00748
Species: Human
Source: HEK293
ST2/IL-1 RL1 Protein, Human, Recombinant
TMPY-00850
Species: Human
Source: HEK293
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
TMPY-00341
Species: Human
Source: HEK293
Clusterin Protein, Human, Recombinant (CLU34, His)
TMPY-01691
Species: Human
Source: HEK293
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TargetMol