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p-Nitrophenyl 2,3,4,6-tetra-O-acetyl-α-D-mannopyranoside is a biochemical reagent essential for glycobiology studies. Glycobiology focuses on the structure, synthesis, biology, and evolution of sugars, encompassing carbohydrate chemistry, glycan formation and degradation enzymology, protein-glycan recognition, and the roles of glycans in biological systems. This field is closely linked to fundamental research, biomedicine, and biotechnology.