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Results for "
1207753-03-4
" in TargetMol Product Catalog- Inhibitors & Agonists1
Ibrexafungerp
GSK 5458448, MK 3118, SCY078, MK3118, SCY-078, GSK5458448
T280511207753-03-4
Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthase inhibitor with antifungal activity, disrupting fungal cell wall integrity, used in fungal infection research.
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T700281965291-14-8
SCY-078 phosphate is a novel glucan synthesis inhibitor.
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T700291965291-08-0
Ibrexafungerp citrate is a triterpenoid antifungal. Similarly to echinocandins, it inhibits the synthesis of 1,3-β-d-glucan. However, it binds to a different site on the enzyme than echinocandins, resulting in limited cross-resistance. Ibrexafungerp exerts concentration-dependent fungicidal activity against Candida species and retains in vitro activity against most fluconazole-resistant strains.
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