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Results for "

11(z),14(z)eicosadienoic acid methyl ester

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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11(Z),14(Z)-Eicosadienoic Acid methyl ester
T3834161012-46-2
11(Z),14(Z)-Eicosadienoic acid methyl ester is a more lipid soluble form of the ω-6 C20-2 fatty acid 11(Z),14(Z)-eicosadienoic acid , a naturally occurring PUFA. 11(Z),14(Z)-Eicosadienoic acid competitively inhibits inosine 5'-monophosphate dehydrogenase (Ki = 3.1 μM) and inhibits the binding of LTB4 to its receptor on neutrophils (Ki = 3.0 μM). Also, serum levels of eicosadienoic acids negatively correlate with degree of sleep disturbance. Eicosadienoic acids are converted by desaturases, in vivo, to eicosatrienoic acids, which are potent vasodilators.
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Corticosterone
Kendall's compound B, Corticosterone (From plants), 17-Deoxycortisol, 11β,21-Dihydroxyprogesterone
T0948L50-22-6
Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active. Corticosterone is involved in the regulation of energy, immune responses, and stress responses in the body.
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TargetMol | Inhibitor Hot
Citronellol
dihydrogeraniol
T3240106-22-9
Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.
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TargetMol | Inhibitor Hot
CRA-026440 hydrochloride
CRA-026440 hydrochloride(847460-34-8 Free base)
T10883L847459-98-7In house
CRA-026440 hydrochloride is a potent and broad-spectrum HDAC inhibitor. CRA-026440 hydrochloride exhibits Ki values against recombinant HDAC isoenzymes HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 are 4 nM, 14 nM, 11 nM, 15 nM, 7 nM, and 20 nM, respectively. CRA-026440 hydrochloride exhibits antitumor and antiangiogenic activities.
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Praeruptorin B
Praeruptorin D
T4S142173069-28-0In house
Praeruptorin B (Praeruptorin D), a compound found in the roots of Peuced, is an inhibitor of sterol regulatory element-binding proteins (SREBPs) that attenuates the metastatic ability of human renal cancer cells by targeting CTSC and CTSV expression, and can be used in the study of osteoporosis.
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7-10 days
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IMPDH2-IN-2
T623381434517-02-8In house
IMPDH2-IN-2 is a potent inhibitor of inosine 5'-monophosphate dehydrogenase (IMPDH) (Ki,app: 14 μM) and a potential anti-tuberculosis agent, exhibiting moderate antibacterial effects with MIC values of 6.3 and 11 μM in minimal GAST Fe and rich 7H9 ADC Tween media, respectively.
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6-8 weeks
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CDK8-IN-12
T720482613307-67-6In house
CDK8-IN-12 is a selective, potent and orally active inhibitor of CDK8 (Ki: 14 nM) and is an anti-cancer agent. CDK8-IN-12 inhibits GSK-3α, GSK-3β and PCK-θ with Ki of 13 nM, 4 nM and 109 nM respectively. CDK8-IN-12 showed anti-proliferative activity against MV4-11 cells.
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UniPR505
T733682938227-14-4In house
UniPR505 is a potent EphA2 antagonist (IC50: 0.95 µM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.
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8-10 weeks
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α-Terpineol
Terpineol
Fr1411598-55-5
Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
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(-)-Isopulegol
Fr1420789-79-2
Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxidant proprieties related to GSH incr
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Uracil
T006966-22-8
Uracil is a common naturally occurring pyrimidine found in RNA, it base pairs with adenine and is replaced by thymine in DNA. Methylation of uracil produces thymine. Uracil's use in the body is to help carry out the synthesis of many enzymes necessary for cell function through bonding with riboses and phosphates. Uracil serves as allosteric regulator and coenzyme for many important biochemical reactions.
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Protocatechuic acid
Protocatechuate, 3,4-Dihydroxybenzoic acid, 3, 4-Dihydroxybenzoic acid
T056299-50-3
Protocatechuic acid (3, 4-Dihydroxybenzoic acid) (3, 4-dihydroxybenzoic acid) is a natural phenolic compound found in many edible and medicinal plants. Recent studies indicate that it could be used as a protective agent against cardiovascular diseases and neoplasms. The mechanism of its action is mostly associated with antioxidant activity, including inhibition of generation as well as scavenging of free radicals and up-regulating enzymes which participate in their neutralization.
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Lactose
T058663-42-3
Lactose is a disaccharide derived from galactose and glucose that is found in milk.
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D-Arabinopyranose
D-arabinose, D(-)-Arabinose
T058828697-53-2
D-(-)-Arabinose is a reducing sugar useful as a substrate in analysis of arabinose isomerases and synthesis of D-erythroascorbic acid in yeast. It shows strong growth inhibition against the Caenorhabditis elegans with an IC50 of 7.5 mM.
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Coumarin
T077591-64-5
Coumarin is a chemical compound poison found in many plants, notably in high concentration in the tonka bean, woodruff, and bison grass. It has clinical value as the precursor for several anticoagulants, notably warfarin.
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Vitamin K1
Phytonadione, Phytomenadione, Phylloquinone, Phyllohydroquinone
T107584-80-0
Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.
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Podofilox
Podophyllotoxin, (+)-Shikonin
T1121518-28-5
Podofilox ((+)-Shikonin) is a lignan (LIGNANS) found in PODOPHYLLIN resin from the roots of PODOPHYLLUM plants. It is a potent spindle poison, toxic if taken internally, and has been used as a cathartic. It is very irritating to skin and mucous membranes, has keratolytic actions, has been used to treat warts and keratoses, and may have antineoplastic properties, as do some of its congeners and derivatives.
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DL-Mevalonolactone
Mevalonolactone
T1353674-26-0
DL-Mevalonolactone, a human endogenous metabolite, is the δ-lactone form of mevalonate, a precursor of the mevalonate pathway. It reduces mitochondrial membrane potential (∆Ψm), Ca2+ retention and NAD(P)H levels in the brain, and also induces mitochondrial swelling.DL-Mevalonolactone induces inflammation and oxidative stress, and reduces mitochondrial membrane potential.
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Hypoxanthine
Sarkin, Sarcine, Purin-6-ol, 6-Hydroxypurine
T136268-94-0
Hypoxanthine (Purin-6-ol), also known as purine-6-ol or Hyp. Hypoxanthine is a naturally occurring purine derivative and a reaction intermediate in the metabolism of adenosine and in the formation of nucleic acids by the nucleotide salvage pathway. Under normal circumstances hypoxanthine is readily converted to uric acid.hypoxanthine is first oxidized to xanthine, which is further oxidized to uric acid by xanthine oxidase.
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Hexadecanal
Palmitaldehyde
T13719629-80-1
Hexadecanal (Palmitaldehyde) is a free fatty aldehyde found in animals.
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7-10 days
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4-Methylumbelliferone
Hymecromone, 4-MU
T139190-33-5
4-Methylumbelliferone (Hymecromone) is a coumarin derivative possessing properties as a spasmolytic, choleretic and light-protective agent. It is also used in ANALYTICAL CHEMISTRY TECHNIQUES for the determination of NITRIC ACID.
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Methoxsalen
Xanthotoxin, NCI-C55903, 8-MOP, 8-Methoxypsoralen
T1548298-81-7
Methoxsalen (NCI-C55903) is a Photoactivated Radical Generator and Psoralen. The mechanism of action of methoxsalen is as a Photoabsorption. The physiologic effect of methoxsalen is by means of Photosensitizing Activity.
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Ethyl oleate
T19316111-62-6
Ethyl oleate, a fatty acid ester produced through the condensation of oleic acid and ethanol, serves as the liquid lipid component in nanostructured lipid carriers (NLCs). These NLCs represent a pioneering approach for the oral administration of trans-Ferulic acid (TFA), highlighting ethyl oleate's critical role in enabling effective drug delivery systems.
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Geniposide
T221224512-63-8
Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation.
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