β-adrenergic receptors agonist

Oxyfedrine L-form HCl (Ildamen) is a partial agonist at beta-adrenergic receptors and acts as a coronary vasodilator and cardiotonic agent.

(±)-Prenalterol (H 80/62) is a new cardioselective positive inotropic compound that is an agonist of beta-2- and beta-1-adrenergic receptors and can be used to study chronic congestive heart failure.

L-Epinephrine is a hormone and neurotransmitter primarily secreted by the adrenal medulla, acting as an agonist for α-adrenergic and β-adrenergic receptors, causing systemic vasoconstriction and cardiac stimulation. It is used to treat glaucoma, allergies, and asthma.

Barbadin is a novel and specific inhibitor of β-arrestin β2-adaptin interaction with an IC50 value of 19.1 μM for β-arestin1 and 15.6 μM for β-arestin2. Barbadin potentiates the long term effects of lorcaserin on POMC neurons and weight loss. Barbadin potentiates the long-term effects of lorcaserin on POMC neurons and weight loss, blocks agonist-promoted endocytosis of prototypic β2-adrenergic, V2-vasopressin, and angiotensin-II-1 receptors, and may be useful in the study of obesity.

BMS-196085 is an effective and selective human β( 3) All agonists of adrenergic receptors, in β( 1) Partial agonist activity was 45%.

Isoetharine mesylate salt (Isoetarine mesilate) is a β-adrenergic receptor agonist. it also is pregnane X receptor (PXR) activator capable of upregulating CYP450 expression.

Nardeterol is a high-affinity, partial agonist for beta adrenergic receptors.

L-Epinephrine (Standard) is the standard substance of L-Epinephrine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. L-Epinephrine is a hormone and neurotransmitter primarily secreted by the adrenal medulla, acting as an agonist for α-adrenergic and β-adrenergic receptors, causing systemic vasoconstriction and cardiac stimulation. It is used to treat glaucoma, allergies, and asthma.

Serpinin, an agonist of the protease inhibitor Nexin-1 (PN-1), upregulates PN-1 expression via the cAMP-PKA-Sp1 signaling pathway, facilitating granule biogenesis in endocrine cells. It is employed in research on secretory function regulation [1]. Serpinin selectively targets β-adrenergic receptors, particularly interacting with β1-adrenergic receptors to activate the AC-cAMP-PKA pathway, thereby regulating myocardial systolic and diastolic function. Additionally, pGlu-serpinin upregulates Bcl2 mRNA transcription and provides neuroprotective effects [2].