(z)-afimoxifene

4-Hydroxytamoxifen (ICI 79280) is the active metabolite of Tamoxifen, an estrogen receptor modulator (SERM) with selective and oral potency. 4-Hydroxytamoxifen has antitumor activity and may be used in breast cancer research.

(E/Z)-4-Hydroxytamoxifen (Afimoxifene) is a novel estrogen inhibitor, commonly used in research for various estrogen-dependent conditions, including cyclic mastalgia and gynecomastia.

(E)-4-Hydroxytamoxifen-d5 ((E)-Afimoxifene-d5) is the deuterated form of (E)-4-Hydroxytamoxifen. (E)-4-Hydroxytamoxifen ((E)-Afimoxifene) acts as an isomer of lower activity compared to (Z)-4-hydroxytamoxifen and functions as a modulator for the estrogen receptor.