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(s) 3,5 dhpg

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Ro 67-4853
Ro67-4853, Ro 674853
T23248302841-89-0
Ro 67-4853 is a selective mGluR1 positive allosteric modulator, enhancing the response to the agonist (S)-3,5-dihydroxyphenylglycine (DHPG) in anesthetized rats through iontophoretic administration.
  • $59
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(S)-3,5-DHPG
T23289162870-29-3
(S)-3,5-DHPG is a weak but selective agonist of group I metabotropic glutamate receptors with Ki values of 0.9 μM for mGluR1a and 3.9 μM for mGluR5a. (S)-3,5-DHPG demonstrates anxiolytic activity in hypoxia-exposed rats, supporting its application in neuropharmacological studies of glutamatergic signaling, stress responses, and anxiety-related behaviors.
  • $143
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