Alkaloids are a class of naturally occurring organic compounds that mostly contain basic nitrogen atoms, produced by a large variety of organisms including bacteria, fungi, plants, and animals. Alkaloids have a wide range of pharmacological activities including antimalarial (e.g. quinine), antiasthma (e.g. ephedrine), anticancer (e.g. homoharringtonine), cholinomimetic (e.g. galantamine), vasodilatory (e.g. vincamine), antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and antihyperglycemic activities (e.g. piperine). Many have found use in traditional or modern medicine, or as starting points for drug discovery. Other alkaloids possess psychotropic (e.g. psilocin) and stimulant activities (e.g. cocaine, caffeine, nicotine, theobromine), and have been used in entheogenic rituals or as recreational drugs. Alkaloids can be toxic too (e.g. atropine, tubocurarine).
Cat No. | product name | ||
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T0486L | Irinotecan Hydrochloride | Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active me... | |
T2714 | Rotundine | Rotundine is extracted from Corydalis yanhusuo W. T. Wang. | |
T3026 | (-)-Huperzine A | Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit... | |
T2S1720 | Huperzine B | 1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for... | |
T8016 | N-Methylbenzylamine | N-Benzylmethylamine is an Alkaloids | |
TN1176 | 10-Nitro-camptothecin | 10-Nitro-camptothecin is a natural product | |
T2718 | Palmatine chloride | Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties. | |
T0022 | Taurine | Taurine, an organic acid, is distributed in various animal tissues. | |
T3243 | Betaine | Betaine is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving bod... | |
T3021 | Bulleyaconitine A | Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels. | |
T5061 | Lumichrome | Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at n... | |
T4S1869 | 12-Epinapelline | 12-Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of ... | |
T3232 | Higenamine hydrochloride | Higenamine(Hydrochloride) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein... | |
TN2325 | (Z)-Akuammidine | (Z)-Akuammidine is a natural product | |
TN1192 | 16-Epivoacarpine | 16-Epivoacarpine is a natural product from Gelsemium elegans. | |
TN1746 | Humantenidine | Standard reference | |
T2725 | Scopolamine hydrobromide | Scopolamine hydrobromide is an alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like A... | |
T2726 | Sinomenine | Sinomenine is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis. | |
TQ0160 | Hydrastine | Hydrastine is a natural alkaloid that is present in Hydrastis Canadensis. | |
T0012 | Cinchonine | Cinchonine, a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local narc... | |
T1174 | Topotecan hydrochloride | Topotecan hydrochloride is an antineoplastic agent used to treat ovarian cancer. | |
T4S0051 | Coptisine sulfate | 1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program. | |
T5595 | Tropine | Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a va... | |
TN1752 | Hydroxyevodiamine | Hydroxyevodiamine is a natural product | |
T5784 | Topotecan | Topotecan is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases. | |
TN1026 | Vomicine | Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals. | |
T4183 | Lavendustin A | lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase. | |
T4036 | Solasodine | Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity again... | |
TJS1226 | Aristolactam I | A natural compound from the herbs of Aristolochia debilis Sieb. et Zucc | |
TN1164 | 1-(3,4-Dimethoxycinnamoyl)piperidine | 1-(3,4-Dimethoxycinnamoyl)piperidine is a natural product | |
T3S0128 | Hydroprotopine | Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable. | |
TN1627 | Euojaponine D | Euojaponine D is a natural product | |
TN2352 | Pingpeimine C | Pingpeimine C Derived from Fritillaria sibiricum. | |
TQ0192 | Senecionine | Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris. | |
T2S2362 | Dehydrocorydaline nitrate | 1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect... | |
T5S0761 | Nitidine chloride | 1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-... | |
T4S0794 | (R)-(+)-Corypalmine | 1. (R)-(+)-Corypalmine shows strong papaverine-like activity. | |
T0690 | Quinine | Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cram... | |
T7786 | Tryptanthrin | Tryptanthrin is a natural DNA gyrase inhibitor。 | |
TN2203 | Senecionine N-oxide | Senecionine N-oxide and senecionine have hepatotoxic activity, no antifertility effects in MeOH extract-treated hamsters. | |
T3S1227 | Aristololactam I | 1. Aristololactam I has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may... | |
TN1925 | Methyl anthranilate | Methyl anthranilate is a natural product | |
T4S0536 | Bullatine A | 1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treat... | |
T1156 | Palonosetron hydrochloride | Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting. | |
T5S0661 | Koumine | 1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a signif... | |
T5765 | Ranaconitine | Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity. | |
T0486 | Irinotecan hydrochloride trihydrate | Irinotecan HCl-trihydrate keeps DNA from unwinding by inhibiting topoisomerase 1. | |
T8182 | Guanfu base A | Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current. | |
T7056 | Dronedarone | Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation. | |
T4953 | Neotuberostemonine | Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)... | |
TN2206 | Shancigusin I | Shancigusin I is a natural from Cremastra appendiculata. | |
T1334 | Hydroquinidine | Dihydroquinidine is an organic compound, used as an antiarrhythmic agent. | |
T1668 | Vinblastine sulfate | Vinblastine sulfate can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM). | |
T2746 | Sophocarpine monohydrate | Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects. | |
TCS2185 | Yohimbine | Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM) | |
T2O2683 | L-Proline | 1. L-Proline is an osmoprotectant. 2. Proline and its derivatives are often used as asymmetric catalysts in organic reactions, as the CBS reduction and proline ... | |
T0186 | Docetaxel trihydrate | Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the the... | |
T1231 | Pilocarpine nitrate | Pilocarpine nitrate is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma. | |
T7097 | Cytochalasin B | Cytochalasin B is a mycotoxin binding to the barbed end of actin filaments. It can disrupt the formation of actin polymers (Kd: 1.4-2.2 nM for F-actin). | |
T2183 | Scopolamine butylbromide | Scopolamine butylbromide is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM). | |
TN2240 | Strictosidinic acid | Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system. | |
TN2370 | 6-Methoxydihydroavicine | 6-Methoxy Dihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxy Dihydrosanguinarine. | |
TN1099 | Dihydroevocarpine | Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a... | |
TN1121 | Evocarpine | Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels. | |
T8161 | Vicine | Vicine, an alkaloid found in fava beans, is toxic in individuals and may cause haemolytic anaemia. | |
T4S0795 | Berberrubine chloride | 1. Berberrubine has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the... | |
T3S2340 | Usaramine | Usaramine demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr. | |
T3S1457 | Palmaturbine | Palmatrubine shows high antitumor activity. | |
T1286 | Vincamine | Vincamine is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cereb... | |
TN2200 | Segetalin A | Segetalin A has estrogen-like activity. | |
T7939 | Fingolimod | Fingolimod is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells). | |
TN1749 | Huperzine C | Huperzine has the value as pretreatment of organophosphate poisoning, it can be used as a protective agent against organophosphate intoxication. | |
TN1340 | 7beta-Hydroxyrutaecarpine | 7beta-Hydroxyrutaecarpine is a natural product from Euodia ruticarpa. | |
T7026 | KukoaMine B | Kukoamine B is a component of Lycii Cortex, with anti-oxidant, anti-acute inflammatory and anti-diabetic properties. | |
TN1444 | Bis(dihydrochelerythrinyl)amine | BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA). | |
T2754 | Oxymatrine | Oxymatrine is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis ... | |
TN1129 | Protostemotinine | Protostemotinine is a natural product from Stemona japonica. | |
T8175 | DL-Laudanosine | Laudanosine is a recognized metabolite of atracurium and cisatracurium. | |
T4116 | Ademetionine | S-ADENOSYL-L-METHIONINE (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma... | |
TN1452 | Broussonetine A | Broussonetines A-H are glycosidase inhibitors. | |
TQ0258 | Corynoxine B | Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese). | |
TN1070 | Aristolochic acid D | Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxic... | |
T0970 | Racanisodamine | Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock. | |
T6S0105 | Peiminine | 1. Peiminine is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury. | |
TQ0264 | Nigakinone | Nigakinone, isolated from Kumu, is one alkaloid with the pharmacological activity. | |
T6S0033 | Crotonoside | 1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats,in decreasing the tone of isolated intestinal strips of the... | |
TN1353 | N-Benzyllinoleamide | (9Z,12Z)-N-Benzyloctadeca-9,12-dienamide is a natural product | |
TJS0123 | Guvacine ethyl ester | Arecoline is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (A... | |
T8185 | (+)-Viroallosecurinine | (+)-Viroallosecurinine is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus. | |
TN1393 | (-)-Anonaine | (-)-Anonaine has some anticancer activity, it induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells, it induces DNA... | |
T2S1200 | Sinapine | 1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant ... | |
T6S2356 | Corynoline | 1. Corynoline is an acetylcholinesterase inhibitor. | |
T5S2357 | Acetylcorynoline | 1. Acetylcorynoline has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of d... | |
TJS0312 | 7-hydroxy-4-methyl-8-nitrocoumarin | ||
T3901 | Solasonine | Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis. | |
T0086 | Galanthamine hydrobromide | Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors. | |
T2764 | (S)-10-Hydroxycamptothecin | 10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma. | |
TN1346 | Oxypalmatine | 8-Oxypalmatine is a natural product | |
TN2023 | 8-Oxoepiberberine | Oxyepiberberine is a natural product | |
TN1142 | 8-Oxocoptisine | 8-Oxycoptisine is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer |