| T0486L |
Irinotecan Hydrochloride |
Irinotecan Hydrochloride is the hydrochloride salt of a semisynthetic derivative of camptothecin. Irinotecan, a prodrug, is converted to a biologically active me...
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| T2714 |
Rotundine |
Rotundine is extracted from Corydalis yanhusuo W. T. Wang.
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| T3026 |
(-)-Huperzine A |
Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit...
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| T2S1720 |
Huperzine B |
1. Huperzine-B is a efficient inhibitor of human brain AChE. 2. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for...
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| T8016 |
N-Benzylmethylamine |
N-Benzylmethylamine is an Alkaloids
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| TN1176 |
10-Nitro-camptothecin |
10-Nitro-camptothecin is a natural product
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| T2718 |
Palmatine chloride |
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
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| T0022 |
Taurine |
Taurine, an organic acid, is distributed in various animal tissues.
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| T3243 |
Betaine |
Betaine is a methyl derivative of glycine first isolated from sugar beets. It has been shown to have potential benefits for fighting heart disease, improving bod...
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| T3021 |
Bulleyaconi cine A |
Bulleyaconitine A, an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels.
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| T5061 |
Lumichrome |
Lumichrome is a natural metabolite of riboflavin. Lumichrome produced by Rhizobium and other bacterial species induces major developmental changes in plants at n...
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| T4S1869 |
12-Epinapelline |
12-Epinapelline is a diterpene alkaloid which displays anaesthetic activity as toxic neurological agents. Similar to aconitine, its suggested that modulation of ...
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| T3232 |
Higenamine Hydrochloride |
Higenamine(Hydrochloride) has been demonstrated to be a β2 adrenoreceptor agonist. Adrenergic receptors, or adrenoceptors, belong to the class of G protein...
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| TN2325 |
(Z)-Akuammidine |
(Z)-Akuammidine is a natural product
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| TN1192 |
16-Epivoacarpine |
16-Epivoacarpine is a natural product from Gelsemium elegans.
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| TN1746 |
Humantenidine |
Standard reference
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| T2725 |
Scopolamine HBr |
Scopolamine hydrobromide is an alkaloid from SOLANACEAE, especially DATURA and SCOPOLIA. Scopolamine and its quaternary derivatives act as antimuscarinics like A...
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| T2726 |
Sinomenine |
Sinomenine is a pure alkaloid isolated from the Sinomenium acutum, is utilized in the treatment of rheumatism and arthritis.
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| TQ0160 |
Hydrastine |
Hydrastine is a natural alkaloid that is present in Hydrastis Canadensis.
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| T0012 |
Cinchonine |
Cinchonine, a local anesthetic of the amide type, now generally used for surface anesthesia. It is one of the most potent and toxic of the long-acting local narc...
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| T1174 |
Topotecan hydrochloride |
Topotecan hydrochloride is an antineoplastic agent used to treat ovarian cancer.
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| T4S0051 |
Coptisine sulfate |
1. Coptisine sulfate has growth inhibitory activity against human cancer cell line in the NCI's anticancer drug screening program.
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| T5595 |
Tropine |
Tropine is a naturally-occurring tropane alkaloid extracted primarily from plants of the Solanaceae family. It serves as an intermediate in the synthesis of a va...
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| TN1752 |
Hydroxyevodiamine |
Hydroxyevodiamine is a natural product
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| T5784 |
Topotecan |
Topotecan is a Topoisomerase I inhibitor,and is an antineoplastic agent used to treat ovarian cancer that works by inhibiting DNA topoisomerases.
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| TN1026 |
Vomicine |
Vomicine is a natural product from Strychnos nux-vomica, the S. nux-vomica extracts show antihyperglycemic activity in experimental animals.
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| T4183 |
Lavendustin A |
lavendustin A is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.
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| T4036 |
Solasodine |
Solasodine(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity again...
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| TJS1226 |
Aristolactam I |
A natural compound from the herbs of Aristolochia debilis Sieb. et Zucc
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| TN1164 |
1-(3,4-Dimethoxycinnamoyl)piperidine |
1-(3,4-Dimethoxycinnamoyl)piperidine is a natural product
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| T3S0128 |
Hydroprotopine |
Hydroprotopine, treatment for coronary heart disease and angina, and the treatment effect is remarkable.
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| TN1627 |
Euojaponine D |
Euojaponine D is a natural product
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| TN2352 |
Pingpeimine C |
Pingpeimine C Derived from Fritillaria sibiricum.
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| TQ0192 |
Senecionine |
Senecionine is the hepatotoxic pyrrolizidine alkaloids isolated from Senecio vulgaris.
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| T2S2362 |
Dehydrocorydaline nitrate |
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect...
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| T5S0761 |
Nitidine chloride |
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-...
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| T4S0794 |
(R)-(+)-Corypalmine |
1. (R)-(+)-Corypalmine shows strong papaverine-like activity.
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| T0690 |
Quinine |
Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cram...
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| T7786 |
Tryptanthrin |
Tryptanthrin is a natural DNA gyrase inhibitor。
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| TN2203 |
Senecionine N-oxide |
Senecionine N-oxide and senecionine have hepatotoxic activity, no antifertility effects in MeOH extract-treated hamsters.
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| T3S1227 |
Aristololactam I |
1. Aristololactam I has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may...
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| TN1925 |
Methyl anthranilate |
Methyl anthranilate is a natural product
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| T4S0536 |
Bullatine A |
1. Bullatine A, a diterpenoid alkaloid of the genus Aconitum, possesses anti-rheumatic, anti-inflammatory and anti-nociceptive effects, may be used for the treat...
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| T1156 |
Palonosetron hydrochloride |
Palonosetron is a 5-HT3 antagonist used in the prevention and treatment of chemotherapy-induced nausea and vomiting.
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| T5S0661 |
Koumine |
1. Koumine can treat the diabetic neuropathy. 2. Koumine has antineoplastic effect, may be a future breast cancer chemotherapeutic agent. 3. Koumine has a signif...
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| T5765 |
Ranaconitine |
Ranaconitine is an important diterpenoid alkaloid from Aconitum sinomontanum Nakai,ranaconitine has cardiotoxicity.
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| T0486 |
Irinotecan hydrochloride trihydrate |
Irinotecan HCl-trihydrate keeps DNA from unwinding by inhibiting topoisomerase 1.
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| T8182 |
Guan-fu base A |
Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6). It also inhibits HERG channel current.
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| T7056 |
Dronedarone |
Dronedarone is an amiodarone analogue which has an effective and promising treatment for Atrial fibrillation.
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| T4953 |
Neotuberostemonine |
Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, it has a significant protective effect on bleomycin (BLM)...
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| TN2206 |
Shancigusin I |
Shancigusin I is a natural from Cremastra appendiculata.
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| T1334 |
Hydroquinidine |
Dihydroquinidine is an organic compound, used as an antiarrhythmic agent.
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| T1668 |
Vinblastine sulfate |
Vinblastine sulfate can inhibit the formation of microtubule, it also inhibits nAChR(IC50=8.9 uM).
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| T2746 |
Sophocarpine monohydrate |
Sophocarpine, a major ingredient of Sophora alopecuroides, has a wide range of pharmacological effects.
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| TCS2185 |
Yohimbine |
Yohimbine is a nonselective alpha 2-adrenergic receptor (AR) antagonist(IC50 : 0.6 μM)
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| T2O2683 |
Proline |
1. L-Proline is an osmoprotectant. 2. Proline and its derivatives are often used as asymmetric catalysts in organic reactions, as the CBS reduction and proline ...
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| T0186 |
Docetaxel trihydrate |
Docetaxel is an antineoplastic agent that has a unique mechanism of action as an inhibitor of cellular mitosis and that currently plays a central role in the the...
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| T1231 |
Pilocarpine nitrate |
Pilocarpine nitrate is a slowly hydrolyzed muscarinic agonist with no nicotinic effects. Pilocarpine is used as a miotic and in the treatment of glaucoma.
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| T7097 |
Cytochalasin B |
Cytochalasin B is a mycotoxin binding to the barbed end of actin filaments. It can disrupt the formation of actin polymers (Kd: 1.4-2.2 nM for F-actin).
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| T2183 |
Scopolamine butylbromide |
Scopolamine butylbromide is a competitive antagonist of mAChR (IC50: 55.3 ± 4.3 nM).
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| TN2240 |
Strictosidinic acid |
Strictosidinic acid has an antiradical action against DPPH, it has a promising effect in the central nervous system.
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| TN2370 |
6- Methoxydihydrosanguinarine |
6-Methoxy Dihydrosanguinarine is an lkaloid isolated from the fruits of M.cordata. 6-Methoxy Dihydrosanguinarine.
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| TN1099 |
Dihydroevocarpine |
Dihydroevocarpine shows potent anti-Helicobacter pylori activity with the minimum inhibitory concentration (MIC) value of 10-20 microg/ml. Dihydroevocarpine is a...
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| TN1121 |
Evocarpine |
Evocarpine shows antimycobacterial, and vasorelaxant effects, it can inhibit Ca2+ influx through voltage-dependent calcium channels.
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| T8161 |
Vicine |
Vicine, an alkaloid found in fava beans, is toxic in individuals and may cause haemolytic anaemia.
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| T4S0795 |
Berberrubine |
1. Berberrubine has antitumor activity. 2. Berberrubine has antidiabetic activity. 3. Berberrubine dose-dependently inhibits IL-8 and MCP-1 protein levels in the...
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| T3S2340 |
Usaramine |
Usaramine demonstrates phytotoxicity against Lactuca sativa var. Carrascoy (lettuce) assessed as inhibition of seed germination at 50 ug/cm2 after 24 hr.
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| T3S1457 |
Palmatrubine |
Palmatrubine shows high antitumor activity.
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| T1286 |
Vincamine |
Vincamine is a major alkaloid of Vinca minor L., Apocynaceae. It has been used therapeutically as a vasodilator and antihypertensive agent, particularly in cereb...
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| TN2200 |
Segetalin A |
Segetalin A has estrogen-like activity.
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| T7939 |
Fingolimod |
Fingolimod is an antagonist of sphingosine 1-phosphate (S1P) (IC50 of 0.033 nM in K562 and NK cells).
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| TN1749 |
Huperzine C |
Huperzine has the value as pretreatment of organophosphate poisoning, it can be used as a protective agent against organophosphate intoxication.
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| TN1340 |
7beta-Hydroxyrutaecarpine |
7beta-Hydroxyrutaecarpine is a natural product from Euodia ruticarpa.
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| T7026 |
KukoaMine B |
Kukoamine B is a component of Lycii Cortex, with anti-oxidant, anti-acute inflammatory and anti-diabetic properties.
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| TN1444 |
Bis[6-(5,6-dihydrochelerythrinyl)]amine |
BIS-[6-(5,6-dihydro-chelerythrinyl)] ether shows strong activity against Aspergillus fumigatus and methicillin-resistant Staphylococcus aureus (MRSA).
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| T2754 |
Oxymatrine |
Oxymatrine is an alkaloid isolated from Sophora flavescens, used as the antibiotic. It is a traditional Chinese medicine used in the treatment against hepatitis ...
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| TN1129 |
Protostemotinine |
Protostemotinine is a natural product from Stemona japonica.
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| T8175 |
Laudanosine |
Laudanosine is a recognized metabolite of atracurium and cisatracurium.
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| T4116 |
Ademetionine |
S-ADENOSYL-L-METHIONINE (SAM) is anti-apoptotic in normal hepatocytes and normal colon epithelial cells but pro-apoptotic in liver human hepatocellular carcinoma...
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| TN1452 |
Broussonetine A |
Broussonetines A-H are glycosidase inhibitors.
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| TQ0258 |
Corynoxine B |
Corynoxine B is a Beclin-1-dependent autophagy inducer. It is an natural alkaloid isolated from Uncaria rhynchophylla (Miq.) Jacks (Gouteng in Chinese).
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| TN1070 |
Aristolochic acid D |
Chinese-herb nephropathy (CHN) is a rapidly progressive renal fibrosis associated with the intake of a Chinese herb (Aristolochia fangchi) containing nephrotoxic...
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| T0970 |
Anisodamine |
Anisodamine is an anticholinergic and α1-adrenergic receptor antagonist used in the treatment of acute circulatory shock.
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| T6S0105 |
Peiminine |
1. Peiminine is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.
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| TQ0264 |
Nigakinone |
Nigakinone, isolated from Kumu, is one alkaloid with the pharmacological activity.
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| T6S0033 |
2-HYDROXYADENOSINE |
1. Crotonoside has much more active than adenosine in reducing the blood pressure in rabbits and cats,in decreasing the tone of isolated intestinal strips of the...
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| TN1353 |
N-Benzyllinoleamide |
(9Z,12Z)-N-Benzyloctadeca-9,12-dienamide is a natural product
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| TJS0123 |
Arecoline |
Arecoline is found in nuts. Arecoline is isolated from betel nuts Arecoline is an alkaloid natural product found in the areca nut, the fruit of the areca palm (A...
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| T8185 |
Viroallosecurinine |
(+)-Viroallosecurinine is a natural alkaloid with antibacterial activity. It exhibits a MIC of 0.48 μg/mL for Ps. Aeruginosa and Staph. aureus.
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| TN1393 |
(-)-Anonaine |
(-)-Anonaine has some anticancer activity, it induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells, it induces DNA...
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| T2S1200 |
Sinapine |
1. Sinapine, an alkaloid from seeds of the cruciferous species, can be used as an effective natural compound for chemo-resistance. 2. Sinapine has antioxidant ...
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| T6S2356 |
(+)-Corynoline |
1. Corynoline is an acetylcholinesterase inhibitor.
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| T5S2357 |
Acetylcorynoline |
1. Acetylcorynoline has antifungal、anti-inflammatory activity. 2. Acetylcorynoline may be one of the potent immunosuppressive agents through the blockage of d...
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| TJS0312 |
7-hydroxy-4-methyl-8-nitrocoumarin |
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| T3901 |
Solasonine |
Solasonine exerts leishmanicidal activity against promastigote forms of L. amazonensis.
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| T0086 |
Galanthamine HBr |
Galanthamine hydrobromide, a long-acting and centrally active AChE inhibitor (IC50:410 nM), is an allosteric potentiator at neuronal nicotinic ACh receptors.
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| T2764 |
10-Hydroxycamptothecin |
10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
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| TN1346 |
8-Oxypalmatine |
8-Oxypalmatine is a natural product
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| TN2023 |
8-Oxoepiberberine |
Oxyepiberberine is a natural product
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| TN1142 |
8-Oxycoptisine |
8-Oxycoptisine is a natural product with Anti-inflammatory, analgesic, cooling, antihypertensive, anti-cancer
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