target/p53/4

p53-Mdm2 inhibitor 4 inhibits the p53-MDM2 protein-protein interaction.

GSNKGAIIGLM(131602-53-4(free base)) (Amyloid beta-peptide(25-35)) is the fragment Aβ(25-35) of the Alzheimer's amyloid β-peptide.

4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.

[D-Pro4,D-Trp7,9,10] Substance P (4-11) is a potent antagonist of the tachykinin family of neuropeptides [1].

[Sar4] Substance P (4-11) is a Substance P agonist and an analog of the C-terminus fragment of Substance P known as Substance P (4-11) [1].

Substance P (4-11), a C-terminal fragment of Substance P, acts as a highly selective agonist for NK1 receptors, demonstrating specificity in its interaction.

(p-Iodo-Phe7)-ACTH (4-10), a derivative of adrenocorticotrophic hormone (ACTH) produced by the anterior pituitary gland, functions as a melanocortin (MC) receptor antagonist and effectively inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats [1].

Butyraldehyde, 4-(p-aminophenoxy)-, diethyl acetal is a bioactive chemical.

Ammonium, (4-(p-ethyldimethylammoniophenyl)butyl)ethyldimethyl-, diiodide can be used in related research in the field of life sciences. Its product number is T30012 and CAS number is 63981-94-2.

m-Toluidine, alpha-((p-chlorophenyl)sulfonyl)-4-(octyloxy)- is a bioactive chemical.

4-Chloro-5-(p-tolyl)-1H-imidazole-2-carbonitrile is a useful organic compound for research related to life sciences and the catalog number is T66379.

Apigenin 4'-O-(2'',6''-di-O-E-p-coumaroyl)glucoside is a natural product for research related to life sciences. The catalog number is TN6304 and the CAS number is 71781-79-8.

Pardaxin P 4 is an antimicrobial peptide found in the secretions of the Red Sea Moses sole (Red Sea Moses sole). It functions as a biolfilm perforating agent, interacting with phospholipid bilayers of varying compositions to induce cytotoxicity and pore formation. Pardaxin P 4 is used in the research of antimicrobial.

[DAla4] Substance P (4-11), an analog of Substance P (Substance P), effectively inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (Eledoisin) and 125I-Bolton Hunter-conjugated Substance P to rat brain cortex membranes, with IC50 values of 0.5 μM and 0.15 μM, respectively [1].

4-(2-(1-(p-Tolyl)ethylidene)hydrazinyl)benzenesulfonamide is a useful organic compound for research related to life sciences. The catalog number is T64550 and the CAS number is 1061214-06-9.

rel-MDM2/4-p53-IN-3 is an MDM2/4-p53 protein-protein interaction (PPI) inhibitor that acts on MDM2-p53 and MDM4-p53 with IC50 values of 18.5 nM and 14.8 nM, respectively. rel-MDM2/4-p53-IN-3 can be used to study cancers, such as colon cancer.

4-(p-Biphenylyl)-3-hydroxybutyric acid is a useful organic compound for research related to life sciences and the catalog number is T124405.

m-Anisidine, 4-((5-p-tolylpentyl)oxy)- is a Drug / Therapeutic Agent.

Acetophenone, 4'-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.

Acetanilide, 4'-(5-(p-(dimethylamino)phenoxy)pentyloxy)-N-ethyl- is a bioactive chemical.

Antimicrobial agent.

[D-Pro4,D-Trp7,9] Substance P (4-11) acts as a potent Substance P antagonist, significantly reducing plasma aldosterone (ALDO) concentrations[1].

2,3,5-Tri-O-(p-toluoyl)-1-O-acetyl-4-thio-D-ribofuranose is a Carbohydrate Derivative.

Benzamide, N-(4-(p-aminophenoxy)butyl)- is a bioactive chemical.

4-Amino-6-bromo-5-cyano-1-(3-deoxy-3-fluoro-2-O-acetyl-5-(O-p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2.3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1038.

Super-chelating agent & MRI contrast agent

Nucleoside Derivatives - 2’-Modified nucleosides, 7-Deaza-purine nucleosides, Halo-nucleosides

3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin is a natural product for research related to life sciences. The catalog number is TN2871 and the CAS number is 349545-02-4.

4-Chloro-5-iodo-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1024.

P-gp inhibitor 4 is a selective P-glycoprotein modulator with an EC 50 of 94 nM. P-gp inhibitor 4 increases drug transport across gastro-intestinal barrier and recovers doxorubicin toxicity in multidrug resistant cancer cells .

m-Anisidine, 4-((5-(p-nitrophenyl)pentyl)oxy)- is a bioactive chemical.

Ammonium, (4-(p-trimethylammoniophenyl)butyl)trimethyl-, diiodide is a bioactive chemical.

4-Chloro-7-(2-deoxy-3,5-bis-O-(p-toluoyl)-b-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine is a useful organic compound for research related to life sciences and the catalog number is TNU1021.

Substance P(1-4) acts as a potent antagonist of neurokinin receptors (NK-R) and regulates normal hematopoiesis, additionally inhibiting the formation of endogenous erythroid colonies (EEC) [1].

3'',4''-Di-O-p-coumaroylquercitrin is a natural product for research related to life sciences. The catalog number is TN5487 and the CAS number is 437615-43-5.

[Tyr(P)4] Angiotensin II is a peptide that affects vascular smooth muscle by causing contraction in normal arteries and inducing hypertrophy or hyperplasia in cultured cells or diseased vessels.

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist that effectively inhibits the actions of gold-protein-substance P (GPSP) and substance P (SP), demonstrating its efficacy in neutralizing their effects [1].

Nucleoside Derivatives - 7-Deaza-8-aza-purine nucleosides; 6-Modified purine nucleosides

Glycolanilide, 4'-(5-(p-aminophenoxy)pentyloxy)- is a bioactive chemical.

Substance P (1-4) is a substance P N-terminal tetrapeptide fragment.

m-Anisidine, 4-((5-((p-chlorophenyl)thio)pentyl)oxy)- is a bioactive chemical.

MDM2/4-p53-IN-2 (2q) is a potent dual inhibitor of MDM2/MDM4 and activator of p53, demonstrating IC50 values of 70.7 nM for MDM2-p53 and 81.4 nM for MDM4-p53 complexes. It facilitates cell cycle regulation, promotes apoptosis, and exhibits anticancer properties [1].

MDM2/4-p53-IN-3, an inhibitor of MDM2/4-p53 protein-protein interactions (PPIs), exhibits potent activity with IC50 values of 18.5 nM for MDM2-p53 and 14.8 nM for MDM4-p53. This compound is applicable in cancer research, including studies on colon cancer [1].

m-Toluidine, 4-(octyloxy)-alpha-(p-tolylsulfonyl)- is a bioactive chemical.

m-Anisidine, 4-((p-(methylsulfonyl)benzyl)oxy)- is a bioactive chemical.

4-O-D-Glucopyranosyl-p-coumaric acid is a useful organic compound for research related to life sciences. The catalog number is T126288 and the CAS number is 117405-49-9.

4''-O-trans-p-Coumaroylafzelin is a natural product for research related to life sciences. The catalog number is TN6121 and the CAS number is 623927-14-0.

3'',4''-Di-O-acetyl-2'',6''-di-O-p-coumaroylastragalin has numerous applications within life science research.