T60146 |
USP8-IN-1
|
2477650-96-5
|
98.01%
|
|
USP8-IN-1 is an inhibitor of USP8 with an IC 50 of 1.9 μM. USP8-IN-1 inhibits H1975 cell growth with a GI 50 of 82.04 μM [1].
|
T11485 |
GSK2643943A
|
2449301-27-1
|
98.06%
|
|
GSK2643943A is a deubiquitylating enzyme (DUB) inhibitor, with an IC 50 of 160 nM for USP20/Ub-Rho. GSK2643943A has anti-tumor efficacy.
|
T11209 |
EOAI3402143
|
1699750-95-2
|
98.09%
|
|
EOAI3402143 is a deubiquitinase (DUB) inhibitor, which inhibits dose-dependently inhibits Usp5/Usp24 andUsp9x.
|
T2424 |
P 22077
|
1247819-59-5
|
98.42%
|
|
P22077 is an inhibitor of ubiquitin-specific protease USP7 with EC50 of 8.6 μM. It also inhibits the closely related USP47.
|
T9217 |
USP7-IN-8
|
2009273-60-1
|
98.48%
|
|
Benzamide, 4-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridinyl]-N-methyl- is a selective ubiquitin-specific protease 7 (USP7) inhibitor with an IC50 of 1.4 μM. US...
|
T4338 |
USP7/USP47 inhibitor
|
1247825-37-1
|
98.5%
|
|
USP7/USP47 inhibitor is a selective ubiquitin-specific protease 7/47 (USP7/USP47) inhibitor, with EC50s of 0.42 μM and 1.0 μM, respectively.
|
T11111 |
DUB-IN-2
|
924296-19-5
|
98.53%
|
|
Dub-in-2, with an IC50 value of 0.28 for USP8, is an effective deubiquitinase inhibitor.
|
T13268 |
USP7-IN-1
|
1381291-36-6
|
98.70%
|
|
USP7-IN-1 is a selective and reversible ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 77 μM) and used for cancer.
|
T9122 |
XL177A
|
2417089-74-6
|
98.75%
|
|
XL177A is a selective irreversible USP7 inhibitor(IC50 : 0.34 nM). XL177A elicits cancer cell killing through a p53-dependent mechanism.
|
T15464 |
HBX 19818
|
1426944-49-1
|
98.76%
|
|
HBX 19818 is a specific ubiquitin-specific protease 7 (USP7) inhibitor (IC50: 28.1 μM).
|
T6107 |
IU1
|
314245-33-5
|
99.11%
|
|
IU1(IC50=4.7 μ M), a reversible, specific human USP14 proteasome inhibitor, can penetrate the cell.
|
T8464 |
RA-9
|
919091-63-7
|
99.31%
|
|
RA-9 is a potent and selective proteasome-associated inhibitor of deubiquitinating enzymes (DUBs), with favorable toxicity profile and anticancer activity. RA-9 ...
|
T7678 |
SJB2-043
|
63388-44-3
|
99.35%
|
|
SJB2-043 is an inhibitor of USP1-UAF1 ( IC50 : 544 nM).
|
T11110 |
DUB-IN-1
|
924296-18-4
|
99.45%
|
|
DUB-IN-1, with an IC50 value of 0.24 for USP8, is an active inhibitor of ubiquitin-specific protease (USPs).
|
T6697 |
TCID
|
30675-13-9
|
99.47%
|
|
TCID(IC50=0.6 μM) is a DUB inhibitor of ubiquitin C-terminal hydrolase L3. It has the 125-fold selectivity to L1.
|
T60130 |
USP5-IN-1
|
|
99.53%
|
|
USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor, which binds to the USP5 ZnF-UBD with a KD of 2.8 μM and is selective over nine proteins contai...
|
T15604 |
IU1-47
|
670270-31-2
|
99.55%
|
|
IU1-47 is an effective and specific USP14 inhibitor (IC50: 0.6 μM). IU1-47 causes tau elimination in cultured neurons. IU1-47 inhibits IsoT/USP5 (IC50: 20 μM).
|
T5461 |
GNE-6640
|
2009273-67-8
|
99.59%
|
|
GNE-6640 is a non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM, 0.43 μM, 20.3 μM and 0.23 μM for full length USP7, US...
|
T3555 |
ML364
|
1991986-30-1
|
99.77%
|
|
ML364 is an inhibitor of ubiquitin specific peptidase 2 (USP2) and can be used for the research of breast cancer.
|
T11464 |
GRL0617
|
1093070-16-6
|
99.77%
|
|
GRL0617 is a selective and competitive SARS-CoVPLpro and deubiquitinase noncovalent inhibitor(IC50 : 0.6 μM, Ki : 0.49 μM).
|