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AChE

Acetylcholinesterase, also known as AChE, AChase or acetylhydrolase, is the primary cholinesterase in the body. It is an enzyme that catalyzes the breakdown of acetylcholine and some other choline esters that function as neurotransmitters. AChE is found at mainly neuromuscular junctions and in chemical synapses of the cholinergic type, where its activity serves to terminate synaptic transmission. It belongs to the carboxylesterase family of enzymes. It is the primary target of inhibition by organophosphorus compounds such as nerve agents and pesticides.
Cat. No. Product name CAS No. Purity Chemical Structure
T7465 4-Methylbenzylidene camphor 36861-47-9 99.59%
4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations ,specifically UV B radiation, also has estrogenic activi...
T3395 Timosaponin AIII 41059-79-4 99.61%
Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibitio...
T4466 Pitofenone hydrochloride 1248-42-6 99.65%
Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36...
T1628 Rivastigmine tartrate 129101-54-8 99.66%
Rivastigmine tartrate is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment o...
T0731 Diethyltoluamide 134-62-3 99.67%
DEET is the most general active composition in insect repellents.
T2571 Benactyzine hydrochloride 57-37-4 99.68%
Benactyzine hydrochloride is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to invest...
T2759 Loganin 18524-94-2 99.7%
Loganin, an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has displayed potent ...
TN1527 (-)-Corynoxidine 57906-85-1 99.73%
(-)-Corynoxidine is an AChE inhibitor derived from tubers of Stephania succifera. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus an...
T2979 DL-Menthol 89-78-1 99.74%
DL-Menthol is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis. (–)-Menthol is more common than (+)-m...
T2S0491 Isoeugenol acetate 93-29-8 99.76%
1. Acetylisoeugenol shows good antifungal activities against R. solani and F. oxysporum. 2. Acetylisoeugenol is a mild sensitizer in vivo.
T0818 Decamethonium bromide 541-22-0 99.79%
Decamethonium Bromide is a neuromuscular blocker and nicotinic AChR partial agonist.
T7041 Donepezil 120014-06-4 99.8%
Donepezil is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate ...
TN1786 Isomerazin 1088-17-1 99.8%
Isomeranzin has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
T1552 Itopride hydrochloride 122892-31-3 99.84%
Itopride hydrochloride is an AChE and D2DR inhibitor.
T0229 Rivastigmine 123441-03-2 99.85%
Rivastigmine is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
T5S2360 Corydaline 518-69-4 99.86%
1. Corydaline, an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and...
T4S1725 Galanthamine 357-70-0 99.87%
Galanthamine is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
T3026 (-)-Huperzine A 102518-79-6 99.87%
Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit...
T1575 Nizatidine 76963-41-2 99.87%
Nizatidine is a competitive and reversible histamine H2-receptor antagonist with antacid activity.
TN1091 Dehydronuciferine 7630-74-2 99.88%
Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn. Dehydronuciferine shows inhibitory of acetylcholinesterase with the IC50 of 25 ug/mL.
4-Methylbenzylidene camphor
T7465
4-Methylbenzylidene camphor is an ultraviolet light blocker used in cosmetics and sunscreen preparations ,specifically UV B radiation, also has estrogenic activi...
Timosaponin AIII
T3395
Timosaponin AIII induces autophagy in HeLa cells followed by apoptotic cell death (IC50: 10 μM). The Timosaponin AIII cellular response is mediated via inhibitio...
Pitofenone hydrochloride
T4466
Pitofenone hydrochloride, a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36...
Rivastigmine tartrate
T1628
Rivastigmine tartrate is a carbamate-derived reversible CHOLINESTERASE INHIBITOR that is selective for the CENTRAL NERVOUS SYSTEM and is used for the treatment o...
Diethyltoluamide
T0731
DEET is the most general active composition in insect repellents.
Benactyzine hydrochloride
T2571
Benactyzine hydrochloride is a centrally acting muscarinic antagonist. Benactyzine has been used in the treatment of depression and is used in research to invest...
Loganin
T2759
Loganin, an iridoid glucoside, has been reported to be an inhibitor of Cox-1 and also noted to suppress TNF-α formation. This compound also has displayed potent ...
(-)-Corynoxidine
TN1527
(-)-Corynoxidine is an AChE inhibitor derived from tubers of Stephania succifera. Corynoxidine exhibits antibacterial activities against Staphylococcus aureus an...
DL-Menthol
T2979
DL-Menthol is a racemic mixture of the monoterpene alcohols (–)-menthol and (+)-menthod, which have been found in Cannabis. (–)-Menthol is more common than (+)-m...
Isoeugenol acetate
T2S0491
1. Acetylisoeugenol shows good antifungal activities against R. solani and F. oxysporum. 2. Acetylisoeugenol is a mild sensitizer in vivo.
Decamethonium bromide
T0818
Decamethonium Bromide is a neuromuscular blocker and nicotinic AChR partial agonist.
Donepezil
T7041
Donepezil is a piperidine-based, potent, specific, and reversible inhibitor of acetylcholinesterase (AChE). It can be used for the treatment of mild to moderate ...
Isomerazin
TN1786
Isomeranzin has anti-inflammatory activity, it suppresses inflammation by inhibiting M1 macrophage polarization through the p65, NF-κB and ERK pathway.
Itopride hydrochloride
T1552
Itopride hydrochloride is an AChE and D2DR inhibitor.
Rivastigmine
T0229
Rivastigmine is a Cholinesterase Inhibitor, used for therapy of Alzheimer disease.
Corydaline
T5S2360
1. Corydaline, an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. 2. Corydaline promotes gastric emptying and...
Galanthamine
T4S1725
Galanthamine is an acetylcholinesterase (AChE)inhibitor(IC50 : 500 nM), can reduce brain damage induced by hypoxia-ischemia.
(-)-Huperzine A
T3026
Huperzine A, an active Lycopodium alkaloid extracted from the traditional Chinese herb, is a potent, selective and reversible acetylcholinesterase (AChE) inhibit...
Nizatidine
T1575
Nizatidine is a competitive and reversible histamine H2-receptor antagonist with antacid activity.
Dehydronuciferine
TN1091
Dehydronuciferine is isolated from the leaves of Nelumbo nucifera Gaertn. Dehydronuciferine shows inhibitory of acetylcholinesterase with the IC50 of 25 ug/mL.
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