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zgn 1061

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  • Inhibitors & Agonists
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Aclimostat
ZGN-1061,Aclimostat
T394902082752-83-6
Aclimostat (ZGN-1061) is a highly potent inhibitor of the MetAP2 enzyme, demonstrating promising efficacy and safety profiles in preclinical trials. In a mouse model of obesity and insulin resistance, ZGN-1061 shows comparable weight loss efficacy to beloranib and improves metabolic parameters. Additionally, ZGN-1061 induces consistent changes in gene transcription in HepG2 cells, further supporting its positive pharmacological effects.
  • $941
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