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Results for "
way213613 hydrochloride
" in TargetMol Product Catalog- Inhibitors & Agonists1
WAY-213613 hydrochloride
WAY-213613 hydrochloride (868359-05-1 free base)
T133302450268-84-3
WAY-213613 hydrochloride is a potent, selective nonsubstrate reuptake inhibitor of GLT-1 EAAT2 with IC 50 of 85 nM. WAY-213613 hydrochloride inhibits EAAT1 and EAAT3 with IC50 values of 5 and 3.8 microM, respectively. WAY-213613 hydrochloride shows no activity at ionotropic and metabotropic glutamate receptors. It is a potential tool for the elucidation of EAAT2 function and can be used for the research of central nervous system [1] [2].
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T13330L868359-05-1
WAY-213613 is a potent and selective nonsubstrate reuptake inhibitor of GLT-1/EAAT2 (IC50: 85 nM EAAT2), displaying 59- and 44-fold selectivity over EAAT1 and EAAT3 (IC50s: 5 and 3.8 μM, respectively). WAY-213613 shows no activity at ionotropic and metabotropic glutamate receptors.
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