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(2)
By Target- HIF/HIF Prolyl-Hydroxylase
- HIF(1)
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- GPR
- LHRH
- Opioid Receptor
- Oxytocin Receptor
- RAAS
- Reductase
- Thyroid hormone receptor(THR)
- 5-HT Receptor
- Adenosine Receptor
- Adiponectin receptor
- Adrenergic Receptor
- Amylin Receptor
- Annexin A
- Apelin receptor
- Arrestin
- Bombesin Receptor
- Bradykinin Receptor
- cAMP
- Cannabinoid Receptor
- CaSR
- CGRP Receptor
- cholecystokinin
- CRFR
- CXCR
- Dopamine Receptor
- EBI2/GPR183
- Endothelin Receptor
- GHSR
- Glucagon Receptor
- GNRH Receptor
- GPCR19
- GPR
- GRK
- GTPase
- Guanylate cyclase
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- Histamine Receptor
- Kisspeptin
- Leukotriene Receptor
- LPA Receptor
- LPL Receptor
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- Melanocortin Receptor
- Melatonin Receptor
- Motilin Receptor
- Neurokinin receptor
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- Neuropeptide Y Receptor
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- AhR
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- HIF/HIF Prolyl-Hydroxylase
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- Hydroxylase
- IDO
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- Hydrolases,EC 3
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By Target By ResearchField- Cardiovascular System(1)
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Results for "
vadadustat
" in TargetMol Product Catalog.- Inhibitors & Agonists3
- Isotope Products1
Vadadustat
PG-1016548, AKB-6548
T46511000025-07-9
Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.
- $42
Size
QTY
Vadadustat-13C2-15N
TMIH-0591
Vadadustat-13C2-15N is 13C and 15N labeled Vadadustat (T4651). Vadadustat ( T4651) has a CAS number of 1000025-07-9. Vadadustat ( T4651) is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.
- $857
Size
QTY
ZG-2686
T2138851795110-22-3
ZG-2686 is a potent and selective agonist of HIF-2α with an EC50 of 0.25 µM, demonstrating selectivity for PHD2. It binds to a specific internal cavity of HIF-2α, forming hydrogen bonds through structural water molecules, which stabilizes the HIF-2α/β heterodimer and enhances its transcriptional activity. The compound acts synergistically with Vadadustat to upregulate HIF-2α-dependent EPO gene expression both in vitro and in vivo. ZG-2686 is applicable for renal anemia research.
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