vacv

Carbenoxolone disodium (Duogastrone) salt is an agent derived from licorice root. It is used for the treatment of digestive tract ulcers, especially in the stomach. Antidiuretic side effects are frequent, but otherwise, the drug is low in toxicity.

ssVACV-70mer sodium is a 70 bp single-stranded oligonucleotide containing a viral DNA motif derived from vaccinia virus DNA. Unlike its double-stranded counterpart, dsVACV 70mer, ssVACV-70mer sodium does not act as an IFN inducer.

dsVACV-70mer sodium is a 70 base pair double-stranded oligonucleotide that contains a viral DNA motif derived from vaccinia virus DNA. It effectively induces IFN-β through a STING-dependent mechanism.

Antiviral agent 33 (compound 1c), a double-stranded DNA (dsDNA) virus inhibitor, exhibits potent inhibitory activity with IC50 values of 0.0790 µM for VACV and 0.1572 µM for AdV5, and is a candidate for oral administration [1].