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Results for "
uk-122
" in TargetMol Product Catalog- Inhibitors & Agonists2
UK-122 TFA salt
UK122 TFA salt, uPA Inhibitor II, UK 122 TFA salt, K122 trifloroacetic acid
T290511186653-73-5
UK-122 is a potent and selective uPA inhibitor (Ki = 20 nM). The IC(50) of UK122 in a cell-free indirect uPA assay is 0.2 micromol L. UK122 showed little cytotoxicity against CFPAC-1 cells (IC(50) > 100 micromol L) but significantly inhibited the migratio
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UK122
UK122
T41085940290-58-4
UK122 is a highly effective and specific inhibitor of urokinase-type plasminogen activator (uPA) with an IC50 value of 0.2 μM. It displays negligible to minimal inhibition towards tissue-type plasminogen activator (tPA), plasmin, thrombin, and trypsin (all IC50 >100 μM). Functioning as a 4-oxazolidinone analogue, UK122 is an anticancer agent that effectively inhibits cancer cell migration and invasion.
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