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By Target- Proteasome
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Results for "
uk-101
" in TargetMol Product Catalog- Inhibitors & Agonists1
UK-101
UK101, UK 101
T132471000313-40-5In house
UK-101 is a potent and selective inhibitor of the immunoproteasome LMP2, inhibiting β1i (LMP2), β1c (LMP2), and β5 (LMP2), with IC50s of 104 nM, 15 μM, and 1 μM, respectively. UK-101 exhibits a 144-fold and 10-fold higher affinity for β1i than for the distribution of β1c and β5 subunits. UK-101 induces apoptosis and can be used to study prostate cancer-related diseases.
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