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By Target- Wnt/beta-catenin
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By Target By ResearchField- Cancer(1)
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Results for "
tnikin1
" in TargetMol Product Catalog.- Inhibitors & Agonists1
TNIK-IN-1
TNIK-inhibitor-1, TNIK inhibitor 1
T26282933886-36-3
TNIK-IN-1 (Compound 1) is a potent inhibitor of Traf2 and Nck-interacting kinase (TNIK), with an IC50 of 65 nM. TNIK is a pivotal effector in the Wnt/beta-catenin signaling pathway, essential for the maintenance of cancer stem cell properties and cellular proliferation. As a lead molecule based on the 4-phenyl-2-phenylaminopyridine scaffold, TNIK-IN-1 demonstrates significant antitumor activity by blocking TNIK kinase function and disrupting oncogenic signaling cascades, making it a valuable tool for researching Wnt-driven malignancies.
- $272
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