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Results for "
tnfαin2
" in TargetMol Product Catalog- Inhibitors & Agonists1
TNF-α-IN-2
T360972074702-04-6
TNF-α-IN-2 is a highly potent and orally bioavailable inhibitor of tumor necrosis factor alpha (TNFα), exhibiting an IC50 of 25 nM in the HTRF assay. It induces conformational changes in the TNFα trimer upon binding, disrupting signaling when the trimer interacts with TNFR1. TNF-α-IN-2 holds promise as a valuable tool for investigating the pathogenesis of rheumatoid arthritis [1].
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