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Results for "
tak960
" in TargetMol Product Catalog- Inhibitors & Agonists2
TAK-960 monohydrochloride
T395532108449-45-0
TAK-960 monohydrochloride is an orally available compound that selectively inhibits polo-like kinase 1 (PLK1) with an IC₅₀ of 0.8 nM. It also demonstrates inhibitory activity against PLK2 (IC₅₀ of 16.9 nM) and PLK3 (IC₅₀ of 50.2 nM), and effectively suppresses the proliferation of various cancer cell lines, exhibiting significant efficacy against multiple tumor xenografts.
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