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syn1143

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SYN1143
RON-IN-1, AMG-1
T8409913376-84-8
SYN1143 (AMG-1) is a potent inhibitor of human RON and c-Met.In vitro kinase assays showed that compound I is a potent inhibitor of human RON and c-Met with IC50s of 9 and 4 nmol L, respectively.
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7-10 days
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AMG-1
T68408903591-53-7
AMG-1 is a specific CRAC channel inhibitor. AMG-1 blocks the function of effector T cells, but not regulatory T cells in vitro and it attenuates the progression and severity of EAE in vivo.
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6-8 weeks
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