sulfamide

Sulfamide (Sulfuric diamide) is used in organic chemistry for synthesis.

Elaidyl-sulfamide is a sulfamoyl analogue of oleoylethanolamide (OEA). ES is a lipid mediator of satiety that acts through the PPARα.

Disulfamide is an orally active carbonic anhydrase inhibitor with an IC50 value of 0.07 μM. Disulfamide has a diuretic effect by inhibiting carbonic anhydrase and preventing the reabsorption of sodium and bicarbonate in the proximal convoluted tubules.

Salazosulfamide has shown potential in the treatment of ankylosing spondylitis, according to research studies.

Vanyldisulfamide, acts as an anti-infective sulfonamide compound.

Azosulfamide is an azo compound with similar antibacterial effect as sulfanilamide.

Phenylsulfamide (Compound 10), acting as an inhibitor of human carbonic anhydrase-II (hCA-II), exhibits a dissociation constant (Kd) of 45.50 μM and an inhibition constant (Ki) of 79.60 μM [1].

Firzacorvir, a cyclic sulfamide compound, functions as an HBV core protein modulator and demonstrates potent anti-HBV activity, with an EC50 value of < 1 μΜ.

DTP348 is an oral dual CAIX inhibitor radiosensitizer. DTP 348 is an oral dual drug with two mechanisms of action: (1). carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components; (2). radio sensitizer of hypoxic cells through its 5-nitroimidazole moiety.

Sultopride is a compound that an amino on the sulfamide group of sulpiride is replaced by an ethyl group.

Glycine, N-[(1,1-dimethylethoxy)carbonyl]thio-L-phenylalanyl-, methyl ester (compound 3b) is a sulfamide-containing polypeptide used in synthesizing peptide-agent coupling compounds [1].