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Search Result
Results for "
separase
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Antibody Products1
Sepin-1
Sepin1, Sepin 1, 2H-Benzimidazole, 2,2-dimethyl-5-nitro-, 1,3-dioxide
T28754163126-81-6
Sepin-1 is a noncompetitive inhibitor of separase (IC50 = 14.8 µM). Sepin-1 can inhibit the growth of breast cancer xenograft tumors in mice and human cancer cell lines by inhibiting cell proliferation and inducing apoptosis.
- $31
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QTY
SIC5-6
T781382410846-16-9
SIC5-6 is a potent inhibitor of Separase, a substantial cysteine protease implicated in critical cellular processes such as chromosome segregation during mitosis and meiosis, DNA damage repair, centrosome disengagement and duplication, as well as spindle stabilization and elongation. Given its overexpression in many solid cancers, Separase presents an attractive target for chemotherapy [1].
- $77
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QTY
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