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sag dihydrochloride

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
SAG dihydrochloride
T404652702366-44-5
SAG dihydrochloride, a powerful agonist of the Smoothened (Smo) receptor (EC 50 = 3 nM; Kd = 59 nM), effectively activates the Hedgehog signaling pathway. It also negates the effects of Cyclopamine inhibition on Smo.
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SAG hydrochloride (912545-86-9(free base))
Smoothened Agonist HCl
T42112095432-58-7
SAG hydrochloride (912545-86-9(free base)) (Smoothened Agonist HCl) acts as an SMO agonist.
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(Rac)-SAG
T85362364590-63-6
(Rac)-SAG, an isoform of SAG, is a potent Smoothened (Smo) receptor agonist (EC₅₀ = 3 nM; Kd = 59 nM) that activates the Hedgehog signaling pathway and counteracts Cyclopamine's inhibition of Smo [1] [2] [3].
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10-14 weeks
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SAG
Smoothened Agonist
T1779912545-86-9
SAG (Smoothened Agonist) is a Smo receptor agonist (EC50=3 nM) that is cell-permeable and selective. SAG regulates Smo activity by binding directly to the Smo helix and can activate the Hedgehog signaling pathway.
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