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rorγt inverse agonist 3

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    6
    TargetMol | Inhibitors_Agonists
RORγt Inverse agonist 3
T127522364429-77-4
RORγt Inverse Agonist 3 is a potent, selective, and orally active inverse agonist of RORγ with EC50 values of 0.22 μM for hRORγ and 0.15 μM for RORγt (human IL-17 cells), respectively.
  • $1,820
8-10 weeks
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QTY
RORγt inverse agonist 32
T2008872301159-96-4
RORγt inverse agonist 32 (compound b14) exhibits oral activity and can be utilized in inflammatory research studies.
  • $1,670
8-10 weeks
Size
QTY
RORγt inverse agonist 34
T2042882247604-77-7
RORγt inverse agonist 34 (compound 5a) is an inverse agonist for RORγt, exhibiting an IC50 of 0.094 μM for the inhibition of RORγt-LBD. This compound is utilized in psoriasis research.
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10-14 weeks
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RORγt inverse agonist 33
T204633
RORγt inverse agonist 33 (compound (R)-D4) is an orally bioavailable RORγt inverse agonist with an IC50 of 21 nM, playing a significant role in rheumatoid arthritis research.
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rorγt inverse agonist 30
T625641445901-41-6
RORγt inverse agonist 30 (Compound 1) is a potent RORγt inverse agonist with an IC50 of 46 nM, making it effective in the treatment of autoimmune diseases by targeting the nuclear receptor RORγt.
  • $1,520
6-8 weeks
Size
QTY
RORγt inverse agonist 31
T79470
RORγt inverse agonist 31 (14g) is a potent antagonist of the retinoic acid receptor-related orphan receptor γt (RORγt), with an inhibitory concentration (IC50) of 0.428 μM. It has shown efficacy in reducing Imiquimod-induced psoriasis severity in murine models [1].
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