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rg13022

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
RG13022
RG 13022, Tyrphostin RG13022
T3545136831-48-6
RG13022 (Tyrphostin RG13022) is a tyrosine kinase inhibitor; inhibits the autophosphorylation reaction of the EGF receptor (IC50: 4 μM).
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TargetMol | Citations Cited
(Z)-RG-13022
(Z)-Tyrphostin RG13022
T84525149286-90-8
(Z)-RG-13022 is a tyrosine kinase (TK) inhibitor that preferentially inhibits the TK activity of the EGF receptor, restricting the EGF-stimulated growth of cultured cells. It demonstrates an IC50 of 11 μM for DNA synthesis in HN5 cells, showcasing thrice the potency of its isomer, (E)-RG-13022 (IC50 = 38 μM). This compound is applied in breast cancer cell research [1] [2].
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8-10 weeks
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