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Results for "
remogliflozin etabonate
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- Isotope Products1
Remogliflozin etabonate
GSK-189075A, GSK189075A, GSK-189075, GSK189075, GSK 189075A, GSK 189075
T34286442201-24-3
Remogliflozin etabonate (GSK189075A) is a prodrug of regaliflozin and an inhibitor SGLT2 with Ki values of 1.95, 2.14, 8.57, and 43.1μM for hSGLT2, rSGLT2, rSGLT1, and hSGLT1, respectively.
- $30
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Remogliflozin etabonate-d7
GSK189075-d7
TMIT-01131233515-93-9
Remogliflozin etabonate-d7 (GSK189075-d7) is a deuterium-labeled form of Remogliflozin etabonate. Remogliflozin etabonate (GSK189075), an orally active, selective, and low-affinity sodium-glucose co-transporter (SGLT2) inhibitor, exhibits Ki values of 1.95 μM for hSGLT2, 43.1 μM for rSGLT2, 2.14 μM for hSGLT1, and 8.57 μM for rSGLT1. As a benzylpyrazole glucoside-based prodrug, it is metabolized in vivo to its active form, Remogliflozin, and demonstrates antidiabetic efficacy in rodent models.
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