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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T9462 | 2-Amino-6-cyclopropylamino-9H-purine | Others | |
2-Amino-6-cyclopropylamino-9H-purine,the key intermediate of abacavir was synthesized from ethyl cyanoacetate by nitrosation,cyclization with guanidine hydrochloride in the presence of EtONa and reduction to give 2,4,5-t... | |||
T39856 | Purine riboside triphosphate | PTP,Purine riboside triphosphate | |
Purine riboside triphosphate, a derivative of purine riboside, exhibits structural similarity to adenosine. This naturally occurring base analog possesses inhibitory effects on carcinogenic growth, particularly in cancer... | |||
T22013 | 8-Aminoadenine | 7H-purine-6,8-diamine,9H-Purine-6,8-diamine | AChR |
8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM. | |||
T7470 | 6-Chloropurine | 6-Chloro-9H-purine | Others |
6-Chloropurine (6-Chloro-9H-purine) is a building block in chemical synthesis,with Antitumor activities. | |||
T36572 | N6-Methyladenine | N6-Methyladenine,6-(Methylamino)Purine | Nucleoside Antimetabolite/Analog |
N6-Methyladenine (6-(Methylamino)Purine) is a modified purine commonly found in genomes of prokaryotes, protists, and plants. N6-methyladenine affects diverse DNA functions, including replication, repair, and expression. | |||
T60390 | PI-55 | 6-(2-hydroxy-3-methylbenzylamino)purine | Others |
PI-55 is a cytokinin receptor inhibitor that exhibits structural similarity to 6-benzylaminopurine (BAP). It competitively inhibits BAP binding on the specific Arabidopsis receptors CRE1/AHK4 and AHK3. Furthermore, PI-55... | |||
T8445 | PU02 | PU-02,6-[(1-Naphthalenylmethyl)thio]-9H-purine | Apoptosis , 5-HT Receptor |
PU02 (6-[(1-Naphthalenylmethyl)thio]-9H-purine) is a potent and selective antagonist of 5-HT3 receptor. | |||
T64944 | 6-(Methylthio)purine | ||
6-(Methylthio)purine is a useful organic compound for research related to life sciences. The catalog number is T64944 and the CAS number is 50-66-8. | |||
T76096 | Purine nucleoside phosphorylase | ||
Purine nucleoside phosphorylase is a key enzyme in purine metabolism, which is involved in the purine rescue pathway. The deficiency of Purine nucleoside phosphorylase resulted in impaired T cell function. In the presenc... | |||
T63738 | Purine phosphoribosyltransferase-IN-2 | ||
Purine phosphoribosyltransferase-IN-2 is a potent inhibitor of Plasmodium falciparum (Pf), Plasmodium vivax (Pv), and Trypanosoma brucei (Tbr) 6-oxopurine phosphoribosyltransferase (PRT) with Ki values of 30, 20, and 2 n... | |||
T63737 | Purine phosphoribosyltransferase-IN-1 | ||
Purinephosphoribosyltransferase-IN-1 (Compound (S,R)-48) is a potent inhibitor of Plasmodium falciparum (Pf), Plasmodium vivax (Pv) and Trypanosoma brucei (Tbr) 6-oxopurine phosphate ribosyltransferase (PRT) with Ki valu... | |||
T21632 | Myoseverin | Others , Microtubule Associated | |
Myoseverin, an inducer of the reversible fission of multinucleated myotubes into mononucleated fragments, affecting the expression of a variety of growth factor, immunomodulatory, extracellular matrix-remodeling, and str... | |||
TNU0907 | 6-Chloro-9-methyl-9H-purine | ||
Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Electrophiles | |||
TNU1104 | 6-Chloro-2-(trifluoromethyl)-9H-purine | ||
Heterocyclic Compounds - Purines; Intermediates and Building Blocks - Nucleoside bases; Multi-functional; Scaffolds and Templates | |||
TNU1211 | 2-Chloro-9-(beta-D-ribofuranosyl)purine | ||
2-Chloro-9-(beta-D-ribofuranosyl)purine is a nucleoside derivative-halo-nucleoside, 6-modified purine nucleoside. | |||
TNU0483 | 6-Methyl-9-(beta-D-xylofuranosyl)purine | ||
Nucleoside Derivatives - Xylo-nucleosides; 6-Modified purine nucleosides | |||
TNU1109 | 2-Methoxy-9-(beta-D-ribofuranosyl)purine | ||
Nucleoside Derivatives - 6-De-aminopurine nucleosides, 2-Modified purine nucleosides | |||
TNU0912 | Benzyl 6-amino-9H-purine-9-acetate | ||
Benzyl 6-amino-9H-purine-9-acetate is a PNA-related derivative. | |||
TNU0669 | 6-Chloro-9-(tetrahydro-2-pyranyl)purine | ||
Intermediate and building block-electrophile, heterocyclic compound-purine | |||
TNU0914 | 6-Benzoylamino-9H-purine-9-acetic acid | ||
6-Benzoylamino-9H-purine-9-acetic acid is a PNA-related derivative, a PNA monomer. | |||
TNU0016 | 6-(Furan-2-yl)purine-beta-D-riboside | ||
6-(Furan-2-yl)purine-beta-D-riboside is a nucleoside derivative-6-modified purine nucleoside. | |||
TNU0095 | 9-(2-C-methyl-β-D-ribofuranosyl)purine | ||
2’-C-Methyl nucleoside; 6-De-aminopurine nucleoside | |||
T9727 | 2'-Fluoro-2'-Deoxyadenosine | Nucleoside Antimetabolite/Analog | |
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex... | |||
TNU0058 | 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)purine | ||
Nucleosides - fluoro nucleoside, 6-deaminopurine nucleoside | |||
TNU0343 | 6-(4-Morpholino)-9-(beta-D-ribofuranosyl)-9H-purine | ||
6-(4-Morpholino)-9-(beta-D-ribofuranosyl)-9H-purine is a nucleoside derivative-6-modified purine nucleoside. | |||
TNU0344 | 6-(1-Piperizinyl)-9-beta-D-ribofuranosyl)-9H-purine | ||
6-(1-Piperizinyl)-9-beta-D-ribofuranosyl)-9H-purine is a nucleoside derivative-6-modified purine nucleoside. | |||
TNU0086 | Purine -9-beta-D-(2’-deoxy-2’-fluoro) arabinoriboside | ||
Fluoro-modified nucleoside; 6-De-aminopurine nucleoside; Arabino-nucleoside | |||
TNU0595 | 2-Amino-6-O-methyl-2’-O-methyl purine riboside | ||
2-Amino-6-O-methyl-2’-O-methyl purine riboside is a nucleoside derivative-6-modified purine nucleoside, 2'-modified nucleoside. | |||
T75072 | 2-Amino-6-O-methyl-2’-O-methyl purine riboside | ||
2-Amino-6-O-methyl-2’-O-methyl purine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely o... | |||
T65626 | 8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione | ||
8-Bromo-3-methyl-1H-purine-2,6(3H,7H)-dione is a useful organic compound for research related to life sciences. The catalog number is T65626 and the CAS number is 93703-24-3. | |||
TNU1411 | 2,6-Bis(4-morpholinyl)-9-b-D-ribofuranosyl-9H-purine | ||
Nucleoside Derivatives –6-Subtituted nucleosides;2-Substituted nucleosides | |||
TNU0491 | 2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine | ||
2-Amino-6-methythio-9-(beta-D-ribofuranosyl)-9H-purine is a nucleoside derivative-6-modified purine nucleoside; thio-nucleoside. | |||
TNU0269 | 6-Methoxy-9-(beta-D-5(R)-methylribofuranosyl)-9H-purine | ||
Nucleoside Derivatives - 5’-Modified nucleoside; 6-Modified purine nucleoside | |||
TNU0101 | 6-Methyl-9-(2-C-Methyl-beta-D-ribofuranosyl) purine | ||
2’-C-Methyl nucleoside; 2/6/8- modified nucleoside | |||
TNU1609 | 6-Mthoxy-9-beta-D-(2-O-methyl-ribofuranosyl)purine | ||
6-Mthoxy-9-beta-D-(2-O-methyl-ribofuranosyl)purine is a nucleoside derivative-6-modified purine nucleoside, 2'-modified nucleoside. | |||
TNU0492 | 2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine | ||
2-Amino-6-allylthio-9-(beta-D-ribofuranosyl)-9H-purine is a nucleoside derivative-6-modified purine nucleoside; thio-nucleoside. | |||
TNU0594 | 6-Ethoxy-9-beta-D-(2-C-methyl-ribofuranosyl)purine | ||
6-Ethoxy-9-beta-D-(2-C-methyl-ribofuranosyl)purine is a nucleoside derivative-6-modified purine nucleoside, 2'-modified nucleoside. | |||
TNU0596 | 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl)purine | ||
6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl)purine is a nucleoside derivative-6-modified purine nucleoside, 2'-modified nucleoside. | |||
T75073 | 6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine | ||
6-Mthoxy-9-beta-D-(2-C-ethynyl-ribofuranosyl) purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process ... | |||
T64613 | 2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione | ||
2-Methoxy-1,7,9-trimethyl-7,9-dihydro-1H-purine-6,8-dione is a useful organic compound for research related to life sciences and the catalog number is T64613. | |||
TNU0182 | 9-(2-Deoxy-β-D-erythropentofuranosyl)-6-methyl-9H-purine | ||
Nucleoside Derivatives - 6-Modified purine nucleosides; Drugs and Inhibitors; Prodrug of anticancer agent 6-methylpurine; used for gene therapy | |||
TNU1427 | 6-Amino-9-[2-deoxy-β-D-ribofuranosyl]-9H-purine | ||
Nucleoside Derivatives - Other modified nucleosides | |||
TNU1278 | 2,6-Dichloro-2',3',5'-triacetyl-purine riboside | ||
2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a nucleoside derivative-halo-nucleoside; scaffold and template. | |||
T8380 | Bendamustine | SDX105 | Apoptosis , Others , DNA Alkylator/Crosslinker |
Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia | |||
TNU0770 | 2-Amino-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)purine | ||
Fluoro-modified nucleoside; 6-De-aminopurine nucleoside | |||
TNU0747 | 6-Chloro-9-(2’,3’-O-isopropylidene-beta-D-ribofuranosyl)purine | ||
Halo-nucleoside; intermediate - electrophile | |||
T2029 | Bohemine | ERK , CDK | |
Bohemine is a cyclin-dependent kinase inhibitor. | |||
TNU0097 | 2-Amino-9-(2-C-methyl-β-D-ribofuranosyl)-9H-purine | ||
2’-C-Methyl nucleoside; 6-De-aminopurine nucleoside | |||
TNU0915 | 2-Amino-6-chloro-9H-purine-9-acetic acid phenyl ester | ||
Intermediates and Building Blocks - Electrophiles; Scaffolds and Templates | |||
TNU0154 | 6-Methoxy-9-(3-deoxy-3-fluoro-b-D-ribofuranosyl)-9H-purine | ||
Nucleoside Derivatives –Fluoro-modified nucleosides, 6-Modified purine nucleosides, 3’-Modified nucleosides |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T4746 | Purine | 7H-Imidazo(4,5-d)pyrimidine | Others , Endogenous Metabolite |
Purine (7H-Imidazo(4,5-d)pyrimidine) is a heterocyclic aromatic organic compound, consisting of a pyrimidine ring fused to an imidazole ring. Two of the bases in nucleic acids, adenine and guanine, are purines. Purines f... | |||
T7444 | 6-(Dimethylamino)purine | N,N-Dimethyladenine | Serine/threonin kinase , CDK |
6-(Dimethylamino)purine (N,N-Dimethyladenine) is a serine threonine protein kinase and CDK inhibitor | |||
T5581 | 6-(γ,γ-Dimethylallylamino)purine | N6-(2-lsopentenyl)adenine,Triacanthine | Others |
6-(γ,γ-Dimethylallylamino)purine (Triacanthine), which is a plant growth substance, shows hypertensive and antitumor activity, also cardiotonic, antispasmodic and a respiratory analeptic. | |||
TNU0052 | Nebularine | 9-(beta-D-Ribofuranosyl)-9H-purine | Apoptosis |
Nebularine (9-(beta-D-Ribofuranosyl)-9H-purine) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting inert lymphoid malignancies and inducing apoptosis.The anticancer mechanism of Nebulari... | |||
T0064 | Adenine | Vitamin B4,6-Aminopurine | DNA/RNA Synthesis , Endogenous Metabolite , AChR |
Adenine (6-Aminopurine), a purine derivative, is a nucleobase with various roles in biochemistry including cellular respiration, in the form of both the energy-rich ATP and NAD and FAD, and protein synthesis, as a chemic... | |||
T8186 | Xanthosine 5'-monophosphate sodium salt | XMP,L-XMP Sodium | Others |
Xanthosine 5'-monophosphate sodium salt (L-XMP Sodium) is an intermediate in purine metabolism. | |||
T6225 | Adenine hydrochloride | Adenine HCl,6-Aminopurine hydrochloride | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry. | |||
T6369 | Adenine hemisulfate | Diadenine sulphate,Adenine sulfate,Adeninsulfat | DNA/RNA Synthesis , Endogenous Metabolite |
Adenine hemisulfate (Diadenine sulphate) is a sulfate salt form of adenine which is a purine derivative and a nucleobase with a variety of roles in biochemistry. | |||
T1004 | 6-Benzylaminopurine | 6-BAP,N6-Benzyladenine,BA,Benzyladenine | Others |
6-Benzylaminopurine (6-BAP), benzyl adenine or BAP is a first-generation synthetic cytokinin that elicits plant growth and development responses, setting blossoms and stimulating fruit richness by stimulating cell divisi... | |||
T19382 | Isoguanine | Nucleoside Antimetabolite/Analog | |
Isoguanine is a purine base that is an isomer of guanine. A building block in organic synthesis. | |||
T7571 | 1-Methyladenosine | Endogenous Metabolite | |
1-Methyladenosine (M1A) belongs to the class of organic compounds known as purine nucleosides. | |||
TQ0273 | Neopterin | D-(+)-Neopterin,2-Amino-6-((1S,2R)-1,2,3-trihydroxypropyl)pteridin-4(3H)-one | Endogenous Metabolite |
D-(+)-Neopterin (D-(+)-Neopterin) is produced by human monocytes/macrophages upon stimulation with the cytokine interferon-γ. In humans, neopterin is involved in purine biosynthesis. | |||
T8075 | 1,3-Dimethyluric acid | Endogenous Metabolite | |
1,3-Dimethyluric acid is a product of theophylline metabolism in man. It is one of the purine components in urinary calculi. | |||
T22218 | 2'-Deoxyguanosine | Deoxyguanosine,Guanine deoxyriboside | Endogenous Metabolite |
2'-Deoxyguanosine (Guanine deoxyriboside) is a purine nucleoside that is recognized by members of the 2'-dG-II family.2'-Deoxyguanosine has been associated with aging, mutation, and carcinogenesis, and is oxidized by mol... | |||
T1362 | Hypoxanthine | 6-Hydroxypurine,Purin-6-ol,Sarcine,Sarkin | Others , Endogenous Metabolite |
Hypoxanthine (Purin-6-ol), also known as purine-6-ol or Hyp, belongs to the class of organic compounds known as purines.Hypoxanthine is a naturally occurring purine derivative and a reaction intermediate in the metabolis... | |||
T1709 | 2'-Deoxyinosine | Guanine deoxyriboside,Deoxyinosine | Others , Endogenous Metabolite |
2'-Deoxyinosine (Guanine deoxyriboside) inhibits the growth of human colon-carcinoma cell lines and is associated with purine nucleoside phosphorylase (PNP) deficiency. | |||
T0543 | 7-Methylxanthine | Heteroxanthine,Heteroxanthin | Nucleoside Antimetabolite/Analog , Endogenous Metabolite |
7-Methylxanthine (Heteroxanthine), a methyl derivative of xanthine, is one of the purine components in urinary calculi. 7-Methylxanthine appears to prevent FDM in pigmented rabbits by remodeling the posterior sclera. | |||
T2A2537 | Guanine | Pearl essence,Mearlmaid,2-Aminohypoxanthine | Others , DNA/RNA Synthesis , Endogenous Metabolite |
Guanine (2-Aminohypoxanthine) is a purine base that is a constituent of nucleotides occurring in nucleic acids. | |||
T2218 | 8-Azaguanine | Azaguanine-8,SK 1150,NSC-749,SF-337 | Nucleoside Antimetabolite/Analog , Others , Endogenous Metabolite |
8-Azaguanine (SK 1150) is a purine analogue with potential antineoplastic activity. | |||
T2993 | Cordycepin | 3'-Deoxyadenosine | MMP , TNF , Antibacterial , Antibiotic , Autophagy |
Cordycepin (3'-Deoxyadenosine) is a purine nucleoside antimetabolite and antibiotic isolated from the fungus Cordyceps militaris with potential antineoplastic activity. | |||
T6523 | Guanosine | DL-Guanosine,Vernine,Guanozin | Endogenous Metabolite , HSV |
Guanosine (DL-Guanosine) is a purine nucleoside formed from a beta-N9-glycosidic bond between guanine and a ribose ring and is essential for metabolism. | |||
T19792 | 1,3,7-Trimethyluric acid | Others | |
1,3,7-Trimethyluric acid is a purine alkaloid that occurs as a minor metabolite of caffeine in humans. As an antioxidant, it has shown an ability to scavenge hydroxyl radicals as well as protective potential against lipi... | |||
T0437 | Inosine | INO 495,NSC 20262 | ROS , Endogenous Metabolite , Adenosine Receptor |
Inosine (NSC-20262) is a purine nucleoside that has hypoxanthine linked by the N9 nitrogen to the C1 carbon of ribose. It has immunomodulatory, neuroprotective, and analgesic properties. | |||
T5073 | Inosine 5'-monophosphate disodium salt hydrate | Inosine 5'-monophosphate disodium salt,5'-IMP-Na2,Disodium 5'-inosinate monohydrate | Others , Endogenous Metabolite |
Inosine 5'-monophosphate disodium salt hydrate (Inosine 5'-monophosphate disodium salt), or inosinic acid, is the ribonucleotide of hypoxanthine and the first nucleotide formed during purine synthesis. | |||
T13539 | Allopurinol riboside | Others , Endogenous Metabolite , Parasite , Drug Metabolite | |
Allopurinol riboside is a metabolite of allopurinol with potency against parasites. Allopurinol riboside competitively inhibits the action of purine nucleoside phosphorylase on inosine with a Ki of 277 μM. | |||
T5282 | 5-Methyluridine | Ribothymidine,Thymine riboside | Others , Endogenous Metabolite |
5-Methyluridine (Thymine riboside) is an endogenous methylated nucleoside found in human fluids; methylated purine bases are present in higher amounts in tumor-bearing patients compared to healthy controls.DNA hypermethy... | |||
T0626 | Uric Acid | 2,6,8-Trioxopurine,2,6,8-Trioxypurine,2,6,8-Trihydroxypurine,Lithic acid,Urate | Reactive Oxygen Species , Endogenous Metabolite , Phosphorylase |
Uric Acid (Lithic acid) is an oxidation product of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE ... | |||
T4685 | INOSINIC ACID | Inosine 5′-monophosphate,IMP,I-5'-P | Endogenous Metabolite |
Inosinic acid (IMP) is a purine nucleotide which has hypoxanthine as the base and one phosphate group esterified to the sugar moiety. Inosinic acid is a nucleotide present in muscle and other tissues. It is formed by the... | |||
T2133 | Adenosine monophosphate | 5'-Adenylic acid,AMP,Adenosine 5'-monophosphate | Endogenous Metabolite , AMPK |
Adenosine monophosphate (AMP) is a purine ribonucleoside 5'-monophosphates and a key cellular metabolite in signal transduction and regulation of energy homeostasis.It has a role as an EC 3.1.3.11 (fructose-bisphosphatas... | |||
T3S2296 | Gardenoside | Others | |
Gardenoside has hepatoprotective, pain‑relieving, and anti-mastitis effects. it may be a potential therapeutic herb against NASH by suppressed supernatant inflammatory cytokine production and intracellular NFkB act... | |||
T0665 | Xanthine | 2,6-Dihydroxypurine,Isoxanthine | Endogenous Metabolite , Adenosine Receptor |
Xanthine (Isoxanthine) is a product on the pathway of purine degradation. Xanthine is subsequently converted to uric acid by the action of the Xanthine oxidase enzyme. Xanthine is found in most body tissues and fluids in... | |||
T4826 | L-Histidine monohydrochloride monohydrat | Others , Endogenous Metabolite | |
Histidine (abbreviated as His or H) is an alpha-amino acid. The L-isomer is one of the 22 proteinogenic amino acids, i.e., the building blocks of proteins. It is classified as a charged, polar because of the hydrophilic ... | |||
T4809 | Pyrimidine | Metadiazine | Others , Endogenous Metabolite |
Pyrimidine (Metadiazine)s are heterocyclic, six-membered, nitrogen-containing carbon ring structures, with uracil, cytosine and thymine being the basal structures of ribose-containing nucleosides (uridine, cytidine, and ... | |||
T4758 | 2'-Deoxycytidine | Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine | Endogenous Metabolite |
2'-Deoxycytidine (Deoxyribose cytidine) is one of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base, without a phos... | |||
T4901 | 5'-Guanylic acid disodium salt | Guanosine 5'-monophosphate disodium salt,GMP-5 | Others , Endogenous Metabolite |
5'-Guanylic acid disodium salt (GMP-5) belongs to the class of organic compounds known as purine ribonucleoside monophosphates. In particular, L-Glutamic acid and guanosine monophosphate can be biosynthesized from xanthy... | |||
T16837 | SAICAR | Others | |
SAICAR is an intermediate of de novo purine nucleotide biosynthesis, activates pyruvate kinase isoform M2 (PKM2) in an isozyme-selective manner (EC50: 0.3 mM). | |||
T35954 | Allantoic acid | ||
Allantoic acid is a degradative product of uric acid and associated with purine metabolism[1][2][3]. [1]. Taherkhani A, et, al. Metabolomic Analysis of Membranous Glomerulonephritis: Identification of a Diagnostic Panel ... | |||
T5084 | Xanthosine dihydrate | 黄苷 | Others , Endogenous Metabolite |
Xanthosine is produced by guanine-free mutants of bacteria e.g. Bacillus subtilis, Aerobacter aerogenes. Xanthosine monophosphate is an intermediate in purine metabolism, formed from IMP, and forming GMP. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02279 | Nucleoside phosphorylase/PNP Protein, Human, Recombinant (His) | Human | E. coli |
Purine nucleoside phosphorylase (PNP) is a purine-metabolizing enzyme that catalyzes the reversible phosphorolysis of 6-oxypurine (deoxy)nucleosides to their respective bases and (deoxy)ribose-1-phosphate. It is a key en... | |||
TMPJ-01308 | ITPase Protein, Human, Recombinant (His) | Human | E. coli |
Inosine Triphosphate Pyrophosphatase (ITPase) is a cytoplasmic enzyme that belongs to the HAM1 NTPase family. ITPase hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP) and deoxyinosine triphosphat... | |||
TMPY-03540 | CD73 Protein, Rat, Recombinant (His) | Rat | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-01342 | CD73 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-01851 | CD73 Protein, Human, Recombinant (His) | Human | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-03377 | CD73 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPJ-00725 | HGPRT Protein, Human, Recombinant (His) | Human | E. coli |
Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed pur... | |||
TMPH-02745 | Kallikrein 8 Protein, Mouse, Recombinant (E. coli, His) | Mouse | E. coli |
This purine-specific ribonuclease cleaves 28S RNA in eukaryotic ribosomes, inhibits protein synthesis, and shows antitumor activity. | |||
TMPH-03190 | CPG2 Protein, Pseudomonas sp., Recombinant (GST) | Pseudomonas sp. | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-00556 | 1-AGPAT Protein, E. coli, Recombinant (His) | E. coli | Yeast |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-03581 | Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) | Staphylococcus epidermidis | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-03233 | HSD17B13 Protein, Rat, Recombinant (E. coli, His) | Rat | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPY-02552 | Adenylosuccinate Lyase Protein, Human, Recombinant (His) | Human | E. coli |
Adenylosuccinate lyase, also known as adenylosuccinase, ADSL or ASL, is an enzyme implicated in the reaction of adenylosuccinat converting to AMP and fumarate as part of the purine nucleotide cycle. The two substates of ... | |||
TMPH-00557 | DXP reductoisomerase Protein, E. coli, Recombinant (His & Myc) | E. coli | E. coli |
Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinos... | |||
TMPH-03535 | Dihydrofolate reductase Protein, S. aureus, Recombinant (His & Myc) | Staphylococcus aureus | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-01111 | COL4A1 Protein, Human, Recombinant (His & SUMO) | Human | E. coli |
Key enzyme in folate metabolism. Contributes to the de novo mitochondrial thymidylate biosynthesis pathway. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. Binds... | |||
TMPY-05454 | CD73 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-06907 | CD73 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPH-00616 | DNA-binding protein H-NS Protein, E. coli, Recombinant (His) | E. coli | E. coli |
mRNA decapping enzyme that specifically removes the nicotinamide adenine dinucleotide (NAD) cap from a subset of mRNAs by hydrolyzing the diphosphate linkage to produce nicotinamide mononucleotide (NMN) and 5' monophosph... | |||
TMPY-05580 | CD73 Protein, Human, Recombinant (hFc) | Human | HEK293 |
5'-nucleotidase, also known as NT5E, NTE, and CD73, is a cell membrane protein that belongs to the 5'-nucleotidase family. CD73 is a glycosylphosphatidylinositol (GPI) anchored purine salvage enzyme expressed on the surf... | |||
TMPY-03332 | PRTFDC1 Protein, Human, Recombinant (His) | Human | E. coli |
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG ... | |||
TMPY-00116 | MTH1 Protein, Human, Recombinant (His) | Human | E. coli |
NUDT1 (Nudix Hydrolase 1) is a Protein Coding gene. The protein encoded by this gene is an enzyme that hydrolyzes oxidized purine nucleoside triphosphates to monophosphates, thereby preventing misincorporation. The NUDT1... | |||
TMPY-03985 | Adenosine Deaminase Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Adenosine Desaminase (ADA) deficiency, is a purine metabolic disorder that cause severe combined immunodeficiency (SCID) due to the accumulation of toxic metabolites that primarily affects development, differentiation a... | |||
TMPH-02885 | SOSTDC1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2. Hydrolyzes adenosin... | |||
TMPH-02294 | UAP1 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely ... | |||
TMPH-01233 | DIP2C Protein, Human, Recombinant (His) | Human | Baculovirus |
Binds galactosides. Has high affinity for the Forssman pentasaccharide. Ligand for HAVCR2/TIM3. Binding to HAVCR2 induces T-helper type 1 lymphocyte (Th1) death. Also stimulates bactericidal activity in infected macropha... |