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psalmotoxin 1

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Psalmotoxin 1
Psalmopoeus cambridgei toxin-1, PcTx1
TP1063880107-52-8
Psalmotoxin 1 is a potent and selective acid-sensing ion channel 1a (ASIC1a) blocker.
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Psalmotoxin 1 TFA
Psalmopoeus cambridgei toxin-1 TFA, PcTx1 TFA
TP3651
Psalmotoxin 1 (PcTx1) TFA is a protein toxin that binds to the subunit interfaces of acid-sensing ion channel 1a (ASIC1a). It selectively and effectively inhibits ASIC1a by enhancing its apparent affinity for H+ (IC50: 0.9 nM). Psalmotoxin 1 TFA induces apoptosis and inhibits cancer cell migration, proliferation, and invasion. This compound is applicable in cancer or neurological disease research.
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