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prmt5 in 9

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
prmt5-in-9
PRMT5-IN-9
T403132691869-52-8
PRMT5-IN-9 is a novel PRMT5 inhibitor for treating cancer, with an IC50 of 0.01 μM.
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PRMT5-IN-1 hydrochloride
T62815
PRMT5 IN-1 hydrochloride (compound 9) is a hemiacetalamine and a potent inhibitor of selective protein arginine methyltransferase 5 (PRMT5), exhibiting an inhibitory effect on PRMT5 MEP50 with an IC50 of 11 nM. Under physiological conditions, it can be converted to an aldehyde and reacts with C449 to form a covalent adduct.
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10-14 weeks
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