plutella xylostella

Azadirachtin B (Deacetylazadirachtinol) is a terpenoid compound isolated from Azadirachta seeds, with insecticidal, anticancer, anti-inflammatory, antitumor, and antiviral activities, useful in the study of viral infections. Azadirachtin B also has osteoblast proliferation, differentiation, and mineralization properties.

Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.

Insecticidal agent 22 (Compound A13) is an insecticide with LC50 values of 1.4 and 9.9 μg/mL against Plutella xylostella and Spodoptera frugiperda, respectively. It serves as a low-toxicity alternative to Fluralaner.

Insecticidal agent 8 is an insecticide with significant biological selectivity against the pea aphid (Aphis craccivoraKoch) and the diamondback moth (Plutella xylostella).

Insecticidal agent 9 (Compound I-17) is an insecticide with strong pest control properties. It exhibits LC50 values of 93.32 mg/L and 114.79 mg/L against Plutella xylostella and Ostrinia furnacalis, respectively. At a concentration of 500 mg/L, it achieves an 86.1% mortality rate for Spodoptera frugiperda. The compound effectively targets ecdysone receptors (EcR) and three chitinase enzymes (OfChtI, OfChtII, and OfChi-h), demonstrating excellent binding activity with EcR and inhibition rates for the chitinases. Insecticidal agent 9 is suitable for research in pest management.

GABA receptor antagonist 2 (Compound IId) is a GABA receptor blocker with an LC50 of 0.0735 μg/mL against Plutella xylostella (P. xylostella). This compound exhibits significant insecticidal activity against P. xylostella and its resistant strains, as well as against Spodoptera frugiperda and Chilo suppressalis. GABA receptor antagonist 2 can bind to the GABA receptor at the Drosophila RdlG335 site and is useful for managing resistant pest populations.

Chitin synthase-IN-15 (Compound 6k) is an inhibitor of chitin synthase and exhibits insecticidal activity against the diamondback moth (Plutella xylostella) with LC50 values of 0.789 and 0.951 μg/mL. It effectively disrupts molting, causes larval death, and leads to abnormal pupation, resulting in a significant reduction in pest populations. Chitin synthase-IN-15 is considered an insecticide with favorable ecological safety.

APS3 is an inhibitor of GABA and nACh receptors, exhibiting an LC50 value of 7.2423 μg/mL against Plutella xylostella [1].

Insecticidal Agent 7 (Compound 21m) is an insecticide that acts on insect ryanodine receptors (RyRs), exhibiting a potency with a LC 50 of 0.0937 mg/L against Plutella xylostella. It demonstrates significant selectivity and minimal toxicity toward non-target organisms [1].

Ailancoumarin E (Compound 5) is a derivative of coumarin. It exhibits deterrent effects against Plutella xylostella and inhibits the growth of its third instar larvae. Additionally, Ailancoumarin E inhibits tyrosinase with an IC50 of 14.21 μM.