piperine

Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.

Tetrahydropiperine (Cosmoperine) is a natural product derived from piperine, can be used to treat convulsion, epilepsy, relieve pain, and control insects.

1-piperoylpiperidine (AI3-01439) is a biochemical.

Lvguidingan is an Anticonvulsant agent.

Piperine (Standard) is a reference standard for research and analysis in studies involving Piperine. Piperine (Bioperine) , a alkaloid, has been used in trials studying the treatment of multiple myeloma and deglutition disorders.

1-piperoylpiperidine (Standard) is a reference standard for research and analysis in studies involving 1-piperoylpiperidine. 1-piperoylpiperidine (AI3-01439) is a biochemical.

Isopiperine is a geometric isomer of Piperine. It can be extracted from pepper and exhibits antifeedant activity against S. litura, with an ED50 value of 0.058 (μmol/cm²).

HJ-4 is a derivative of Piperine. It effectively inhibits the proliferation of colorectal cancer (CRC) cells by reducing colony formation and DNA synthesis in a dose-dependent manner. HJ-4 notably impairs the adhesion, migration, and invasion of CRC cells and induces apoptosis. In a chicken embryo chorioallantoic membrane (CAM) model with implanted HCT116/SW480 tumor spheroids, HJ-4 demonstrates antitumor efficacy. HJ-4 is applicable for colorectal cancer (CRC) research.

1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.

Methylpiperic acid, a piperine alkaloid, exhibits potent inhibitory activity on monoamine oxidase (MAO), with differing efficacy on isoforms: greater inhibition of MAO-A (IC 50 27.1 μM) compared to MAO-B (IC 50 1.6 μM), indicative of its bidirectional inhibition. Moreover, it is applied in the treatment of mental disorders [1].

Linarin (Standard) is a reference standard for research and analysis in studies involving Linarin. 1. Linarin (Acacetin-7-O-rutinoside) (acacetin-7-O-β-d-rutinoside) shows selective dose dependent inhibitory effect on acetylcholinesterase. 2. Linarin alleviates GalN/LPS-induced liver injury by suppressing TNF-α-mediated apoptotic pathways. 3. Linarin prevents A beta-induced neurotoxicity through the activation of PI3K/Akt, which subsequently inhibits GSK-3b and up-regulates Bcl-2. 4. The piperine significantly enhanced the oral absorption of Linarin in rats by inhibiting P-glycoprotein mediated cellular efflux during the intestinal absorption and likely simultaneously by inhibiting the metabolism of Linarin.