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By Target- Ligands for Target Protein for PROTAC
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Results for "
pin1-3
" in TargetMol Product Catalog- Inhibitors & Agonists3
PIN1 inhibitor 3
T2007293039570-04-9
PIN1 inhibitor3 (Compound A0) is a PIN1 inhibitor with a dissociation constant (KD) of 25 nM and a half-maximal inhibitory concentration (IC50) of 150 nM. It serves as a target protein ligand for PROTAC synthesis and is applicable in cancer research.
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BJP-07-017-3
T2045102468783-22-2
BJP-07-017-3 is an inhibitor of proline cis-trans isomerase (Pin1) with an IC50 of 9 nM. It forms a covalent bond with Cys113 of Pin1, inducing conformational changes that decrease its stability and lead to proteasome-dependent degradation.
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sulfopin
Acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(tetrahydro-1,1-dioxido-3-thienyl)-
T92402451481-08-4
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
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