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By Target By ResearchField- Cancer(2)
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Results for "
pin1-3
" in TargetMol Product Catalog.- Inhibitors & Agonists4
sulfopin
Acetamide, 2-chloro-N-(2,2-dimethylpropyl)-N-(tetrahydro-1,1-dioxido-3-thienyl)-
T92402451481-08-4
Sulfopin is a highly selective covalent inhibitor of Pin1 with an apparent Ki of 17nM. Sulfopin blocks Myc-driven tumors in vivo.
- $30
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BJP-07-017-3
T2045102468783-22-2
BJP-07-017-3 is an inhibitor of proline cis-trans isomerase (Pin1) with an IC50 of 9 nM. It forms a covalent bond with Cys113 of Pin1, inducing conformational changes that decrease its stability and lead to proteasome-dependent degradation.
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PIN1 degrader-3
T2140763101950-55-1
PIN1degrader-3 is a degrader of Pin1 (peptidyl-prolyl isomerase protein) with an IC50 of 4.65 nM. It covalently binds to Pin1 and destabilizes it in vitro, leading to its degradation within cells. PIN1degrader-3 can be utilized in pancreatic cancer research.
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