photosensitivity

Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resulting in a decreased formation of precursors of prostaglandins and thromboxanes.

Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.

Lemuteporfin is a light-activated photosensitizing agent that is rapidly internalized by viable cells, localizing within the cytoplasm and associating with mitochondria. This localization is a key characteristic that confers strong cytotoxic potential upon light activation. Lemuteporfin has demonstrated the ability to reduce sebaceous gland volume in preclinical animal studies. It is currently under investigation in relation to benign prostatic hyperplasia and in topical form for the management of androgenetic alopecia.

4,5'-Dimethylangelicin-NHS is an NHS-containing, modified 4,5'-Dimethylangelicin. 4,5'-Dimethylangelicin is a carbofuran coumarin that exhibits photochemical and photosensitivity properties. 4,5'-Dimethylangelicin has the potential to be a photochemical agent.

Hyaluronic acid Methacryloyl (MW 400 kDa) is a methacrylated form of hyaluronic acid that exhibits biocompatibility. It functions as a 3D printing hydrogel ink, characterized by rapid photosensitivity, quick gelation speed, and stable hydrogel properties. Upon UV exposure, it can rapidly initiate gelation with lithium phenyl-2,4,6-trimethylbenzoylphosphinate (LAP). Additionally, when combined with tissue-specific extracellular matrix (ECM) materials, such as pancreatic extracellular matrix (pECM), Hyaluronic acid Methacryloyl (MW 400 kDa) serves as a crucial source material for organoid culture.

Deuteroporphyrin IX (dihydrochloride) is a photosensitizer known for its high lipophilicity and amphiphilicity, which enables it to impart photosensitivity to cell membrane systems. Additionally, Deuteroporphyrin IX (dihydrochloride) can induce irreversible discharge elimination in individual neurons.