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phosphomannose isomerase

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  • Inhibitors & Agonists
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Phosphomannose isomerase
T799289023-88-5
Phosphomannose isomerase, the initial enzyme in GDP-Man biosynthesis, catalytically facilitates the interconversion of fructose-6-phosphate (Fru6P) and mannose-6-phosphate (Man6P), playing a crucial role in cell wall synthesis and protein glycosylation. It is also recognized as a significant antifungal target against threats from A. flavus [1].
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ML089
T603521306638-12-9
ML089 (CID-22416235) is an orally available and potent, selective inhibitor of phosphomannose isomerase (PMI), with potential inhibition of other PMI immediate homologs.ML089 is a membrane-permeable probe for the study of congenital dysglycosylation type Ia (CDG-Ia).
  • $52
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MLS0315771
T16118727664-91-7
MLS0315771 is an effective and biologically active competitive phosphomannose isomerase (MPI) inhibitor (IC50: ~1 μM and a Ki: 1.4 μM).
  • $48
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