phosphatidylcholine

Palmitoyldocosahexaenoyl phosphatidylcholine is a polyunsaturated fatty acid that mimics special cell membrane structural domain lipids.

Phosphatidylcholines,soya (Soybean phosphatidylcholine) is a phosphatidylcholine from soybean used in the preparation of liposomes.

Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Exogenous administration of citicoline to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.

Lecithin (L-alpha-phosphatidylcholine) is considered a safe source of conventional phospholipids. Phospholipids can change the fatty acid composition and microstructure of animal cell membrane.

1-(1(Z)-Hexadecenyl)-2-palmitoleoyl-sn-glycero-3-phosphocholine is a plasmalogen characterized by the presence of 1(Z)-hexadecenoic acid and palmitoleic acid located at the sn-1 and sn-2 positions, respectively.

1,2-Dimyristoyl-sn-glycero-3-phosphocholine (DMPC) is a synthetic phospholipid utilized in liposomes for the study of lipid monolayers and bilayers.

Lysophosphatidylcholine 18:2 is a mouse metabolite functionally related to linoleic acid.18:2 LysoPC is a major component of oxidized low-density lipoproteins (LDLs), and low plasma levels of LPC 18:2 have been associated with metabolic disorders such as impaired glucose tolerance, insulin resistance, type 2 diabetes, and coronary artery disease.1-Linoleoyl 1-Linoleoyl-2-Hydroxy-sn-glycero-3-PC is also a substrate for the generation of lysophosphatidic acid (LPA) from Autotaxin (LysoPLD), which plays an important role in cell motility.

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) is a phospholipid commonly found in cell membranes, with cholesterol compositions ranging from 0 to 60 mol%.

1-Stearoyl-sn-glycero-3-phosphocholine (L-ALPHA-LYSOPHOSPHATIDYLCHOLINE, STEAROY) is a chemical compound utilized in lipid metabolism studies.

Citicoline (CDP-Choline) is an intermediate in the synthesis of phosphatidylcholine, a component of cell membranes. Citicoline exerts neuroprotective effects.

Phosphatidylserine is a phospholipid naturally present in mammals, exhibiting anti-inflammatory and anti-atherosclerotic effects. It activates PKC, neutral sphingolipidase, C-raf-1 protein kinase, and other cofactors involved in multiple signaling pathway activations.

Lyso-globotriaosylceramide is a form of globotriaosylceramide that is lacking the fatty acyl group. It binds to Shiga toxin 1 (Stx1) in the presence of cholesterol and phosphatidylcholine but does not bind Stx2. It also reduces viability and aggregation of human neutrophils induced by phorbol 12-myristate 13-acetate when used at concentrations of 50 and 1 μM, respectively. Lyso-globotriaosylceramide accumulates in the brain, heart, kidney, liver, lung, and spleen in a mouse model of Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. It also accumulates in the urine, kidney, and plasma of patients with Fabry disease. Lyso-globotriaosylceramide levels decrease in response to administration of the α-galactosidase inhibitor 1-deoxygalactonojirimycin in a transgenic mouse model of Fabry disease. Decreases in plasma and urine concentrations of lyso-globotriaosylceramide have been used as a biomarker for efficacy of enzyme replacement therapy (ERT) and other therapies in the treatment of Fabry disease.

1-Oleoyl-2-palmitoyl-sn-glycero-3-phosphatidylcholine (PC), derived from oleic acid, is used in liposome synthesis [1].

Citicoline sodium (Standard) is the standard substance of Citicoline sodium, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Citicoline sodium (CDP-choline) is an endogenous intermediate in the synthesis of phosphatidylcholine. It also serves as a choline donor in the biosynthesis of the neurotransmitter acetylcholine. Citicoline sodium demonstrates protective effects in cerebral ischemia, traumatic brain injury, and memory disorders. Exogenous administration of citicoline to rodents (500 mg/kg i.p. immediately after ischemia and at 3-h reperfusion) has been shown to stimulate the synthesis of phosphatidylcholine, sphingomyelin, and cardiolipin and to attenuate the release of arachidonic acid and the accumulation of ceramide.

Glycerophosphocholine ((S)-Glycerolphosphocholine) is an intracellular metabolite involved in the metabolism of phosphatidylcholine and is utilized for studying the endogenous choline supply within cells. Additionally, Glycerophosphocholine serves as a supplement in research focused on brain-related disorders.