peptide deformylase pdf

Actinonin is a natural antibacterial agent produced by Streptomyces, also serving as an effective PDF (peptide deformylase) inhibitor and apoptosis inducer. It inhibits APN (Aminopeptidase N), MMPs and heparin α, exhibiting antiproliferative and antitumour activity.

Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).

PDF-IN-2 is an inhibitor of peptide deformylase (PDF). It exhibits average IC50 values of 0.25, 0.50, and 0.34 nM against Streptococcus pneumoniae strains PDFWT, G70V, and G70D, respectively, with corresponding average MIC values of 0.16, 0.33, and 0.25 μg/mL. PDF-IN-2 is applicable for research in infectious diseases.

FR-202306 is a inhibitor of peptide deformylase (PDF).

LBM-415 is a peptide deformylase (PDF) inhibitor.