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By Target- SARS-CoV
- ALK(1)
- Autophagy(1)
- ROS Kinase(1)
- Trk receptor(1)
- Others(1)
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By Target By ResearchField- Inflammation(1)
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Results for "
paquinimod
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Isotope Products2
Paquinimod
Cited
ABR 25757
T7310248282-01-1
Paquinimod (ABR 25757) is a S100A9 inhibitor preventing S100A9 binding to TLR-4.
- $36
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CitedPaquinimod-d5-1
TMID-0832
Paquinimod-d5-1 is the deuterated form of Paquinimod. Paquinimod (ABR 215757) is an orally active, specific inhibitor of S100A8/S100A9, used in studying pneumonia by reducing viral load in mice infected with SARS-CoV-2.
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Entrectinib-d4
TMID-0624
Entrectinib-d4 is the deuterium-labeled isotope of Paquinimod. Entrectinib is an orally active inhibitor of TrkA/B/C, ROS1, and ALK, capable of crossing the blood-brain barrier and possessing central nervous system activity, with IC50 values of 1, 3, 5, 12, and 7 nM, respectively. It induces apoptosis and cell cycle arrest in cancer cells, exhibits antitumor efficacy, and mitigates bleomycin-induced pulmonary fibrosis in mice.
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