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Results for "
pactimibe
" in TargetMol Product Catalog- Inhibitors & Agonists2
Pactimibe
CS-505, CS505, CS 505, Pactimibe free base
T28290189198-30-9
Pactimibe is a ACAT inhibitor. It has anti-atherosclerotic activity.
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pactimibe sulfate
T62974608510-47-0
Pactimibe sulfate (CS-505) is a dual ACAT1 2 inhibitor, acting on ACAT1 (IC50: 4.9 μM) and ACAT2 (IC50: 3.0 μM). It inhibits oleoyl-CoA non-competitively (Ki: 5.6 μM) and significantly inhibits cholesterol ester formation (IC50: 6.7 μM). Pactimibe sulfate reduces plasma cholesterol activity and has anti-atherogenic potential.
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