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Hydrangenol is a natural product and can be isolated from Hydrangea serrata leaves. Hydrangenol is an antiphotoaging compound with oral activity. Hydrangenol can reduce MMP and inflammatory cytokine expression and increase moisturizing factors and antioxidant genes level, result in preventing wrinkle formation.

Kaempferol-7-O-β-D-glucopyranoside (Kaempferol-7-O-D-glucopyranoside), a novel supercoolant, could be used for sub-zero, non-freezing preservation of rat hearts.

Sanggenon D (Sanggenone D), a small molecule compound from Morus alba Bark, is a GABA(A) receptor modulator with antioxidant and antibacterial activity, inhibits breast cancer cell proliferation, and inhibits the growth of Staphylococcus aureus by modulating the fatty acid biosynthesis system.

Sappanone A is a high isoflavanone that exhibits anti-inflammatory effects by modulating Nrf2.Sappanone A attenuates allergic airway inflammation in ovalbumin-induced asthma.

2',3,5,6',7-Pentahydroxyflavanone (3,5,7,2',6'-Pentahydroxyflavanone) is a natural product isolated from the roots of *Scutellaria baicalensis*.

5-Hydroxy-7,8-dimethoxyflavanone is isolated from Andrographis paniculata Nees. leaves and roots with anti-inflammatory activity.

2-Ethylpyrazine is present in roasted coffee beans and is a volatile compound .2-Ethylpyrazine induces vasodilation through the activity of endothelium-derived relaxing factors.2-Ethylpyrazine activates NO synthesis through the action of endothelial endothelial NO synthase.2-Ethylpyrazine induces vasodilation by inducing NO release and increasing peripheral blood flow to induce vasodilation.

(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) is a potential inhibitor of the mitogen-activated phosphor kinase pathway and an anti-inflammatory agent first isolated from the medicinal plant S. tuberosa. Additionally, it shows promising anthelmintic activity against Haemonchus contortus.

Ilexgenin A is a novel pentacyclic triterpenoid, is a compound extracted from leaves of Ilex hainanensis Merr

Epibetulinic acid has anti-inflammatory activity, it exhibits potent inhibitory effects on NO and prostaglandin E(2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin.

Karanjin is a flavonoid obtained from the seeds of the karanja tree.Karanjin induces GLUT4 translocation in skeletal muscle cells by increasing AMPK activity. Karanjin can induce cancer cell death through cell cycle arrest and enhance apoptosis.

Taraxasterol (Taraxasterin) is compound with anti-inflammatory activity.

Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.

Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxant activities, and attenuates Aβ1-42-induced oxidative stress and apoptosis by inducing autophagy.SB-674042 is used for the treatment of depression.SB-674042 is used for the treatment of depression.SB-674043 is used for the treatment of depression.SB-674044 is used for the treatment of depression.SB-674045 is used for the treatment of depression. 2A (BU-1) cell differentiation.

Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and/or release of dopamine, to act through central dopamine2 receptor, which in turn causes the release of PGs.

Myristicin (Myristicine) is a natural product found in spices and umbelliferous plants. Myristicin has anti-cholinergic, Antibacterial, and hepatoprotective effects, it also has anti-inflammatory properties related with its inhibition of NO, cytokines,chemokines, and growth factors in dsRNA-stimulated macrophages via the calcium pathway. Myristicin can induce Apoptosis as characterised by alterations in the mitochondrial membrane potential, cytochrome c release, Caspase-3 activation, PARP-cleavage and DNA fragmentation.

Protosappanin A (PTA) has anti-oxidative/nitrative activities on brain immune and neuroinflammation through regulation of CD14/TLR4-dependent IKK/IκB/NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM.

Cyanidin 3-sambubioside chloride (Cyanidin-3-O-sambubioside chloride) is a plant-derived anthocyanin, an inhibitor of NO and H274Y mutations, and an inhibitor of influenza neuraminidase.Cyanidin 3- sambubioside chloride has anti-inflammatory properties. sambubioside chloride has antioxidant, antiangiogenic and antiviral activities and inhibits angiotensin-converting enzyme (ACE) activity, which can be used in the study of viral infections and cardiovascular diseases.

Bavachromene, an isoprenylated chalcone extractable from Fructus in the family Psoraceae, has estrogenic and antimicrobial activities, and concentration-dependent inhibition of Lipopolysaccharide (LPS)-activated NO and PGE2 production in microglia.

5,7,8-Trimethoxyflavone (Norwogonin 5,7,8-trimethyl ether) is a compound extracted from *Andrographis paniculata*, exhibiting anti-inflammatory activity and NO inhibition.

4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg/mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methoxycinnamyl alcohol did not show apoptotic effects but showed necrosis after 48 h in a 10 μg/mL DNA fragmentation study.

Catalposide is a potent inducer of (HO)-1 isolated from Catalpa ovate G. Don (Bignoniaceae). Catalposide possesses antioxidant, anti-apoptotic, anti-microbial, anti-tumoral, and anti-inflammatory properties.

Ergosta-7,22-dien-3-one is a lanosterane that can be isolated from the substrates of Ganoderma taiwanensis. It exhibits pro-inflammatory properties, stimulating nitric oxide production, inducing gene expression, and promoting the production of TLRs, cytokines, chemokines, and cellular adhesion molecules.

Erythro-Guaiacylglycerol beta-coniferyl ether is a compound that can be extracted from the stems and leaves of mung beans and has inhibitory effects on alpha-glucosidase with an EC50 value of 18.71 μM.