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Hydrangenol
TN4234480-47-7In house
Hydrangenol is a natural product and can be isolated from Hydrangea serrata leaves. Hydrangenol is an antiphotoaging compound with oral activity. Hydrangenol can reduce MMP and inflammatory cytokine expression and increase moisturizing factors and antioxidant genes level, result in preventing wrinkle formation.
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Sanggenon D
Sanggenone D
T4S161681422-93-7
Sanggenon D (Sanggenone D), a small molecule compound from Morus alba Bark, is a GABA(A) receptor modulator with antioxidant and antibacterial activity, inhibits breast cancer cell proliferation, and inhibits the growth of Staphylococcus aureus by modulating the fatty acid biosynthesis system.
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7-10 days
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2',3,5,6',7-Pentahydroxyflavanone
3,5,7,2',6'-Pentahydroxyflavanone
TN268980366-15-0
2',3,5,6',7-Pentahydroxyflavanone (3,5,7,2',6'-Pentahydroxyflavanone) is a natural product isolated from the roots of *Scutellaria baicalensis*.
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7-10 days
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Kaempferol-7-O-β-D-glucopyranoside
Kaempferol-7-O-D-glucopyranoside
T407316290-07-6
Kaempferol-7-O-β-D-glucopyranoside (Kaempferol-7-O-D-glucopyranoside), a novel supercoolant, could be used for sub-zero, non-freezing preservation of rat hearts.
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(E)-Ferulic acid methyl ester
Methyl ferulate, Methyl (E)-ferulate
T3S000622329-76-6
(E)-Ferulic acid methyl ester (Methyl (E)-ferulate) is a potential inhibitor of the mitogen-activated phosphor kinase pathway and an anti-inflammatory agent first isolated from the medicinal plant S. tuberosa. Additionally, it shows promising anthelmintic activity against Haemonchus contortus.
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Euxanthone
1,7-Dihydroxyxanthone
T4001529-61-3
Euxanthone (1,7-Dihydroxyxanthone), an xanthone derivative extracted from the roots of Polygala tenuifolia Willd, has antitumour, neuroprotective and vasorelaxant activities, and attenuates Aβ1-42-induced oxidative stress and apoptosis by inducing autophagy.SB-674042 is used for the treatment of depression.SB-674042 is used for the treatment of depression.SB-674043 is used for the treatment of depression.SB-674044 is used for the treatment of depression.SB-674045 is used for the treatment of depression. 2A (BU-1) cell differentiation.
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6-8 weeks
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Escin IB
T5S138926339-90-2
Escin Ib inhibits gastric emptying, at least in part, mediated by capsaicin-sensitive sensory nerves, to stimulate the synthesis and or release of dopamine, to act through central dopamine2 receptor, which in turn causes the release of PGs.
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Erythro-Guaiacylglycerol beta-coniferyl ether
TN4003890317-92-7
Erythro-Guaiacylglycerol beta-coniferyl ether is a compound that can be extracted from the stems and leaves of mung beans and has inhibitory effects on alpha-glucosidase with an EC50 value of 18.71 μM.
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Goniothalamin
TN416017303-67-2
Goniothalamin induces apoptosis in various cancer cell lines and has gastroprotective activity.
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Protosappanin A
PTA
TJS1779102036-28-2
Protosappanin A (PTA) has anti-oxidative nitrative activities on brain immune and neuroinflammation through regulation of CD14 TLR4-dependent IKK IκB NF-κB inflammation signal pathway; it exerts anti-neuroinflammatory effect by inhibiting JAK2-STAT3 pathway in lipopolysaccharide-induced BV2 microglia. Protosappanin A induces immunosuppression of rats heart transplantation targeting T cells in grafts via NF-kappaB pathway. Protosappanin A and protosappanin B have antimicrobial activity, they show both alone activities and resistance reversal effects of amikacin and gentamicin against MRSA. Protosappanin A shows strong effect against HIV-1 IN with an IC50 value of 12.6 uM.
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4-Methoxycinnamyl alcohol
TN304953484-50-7
4-Methoxycinnamyl alcohol showed toxicity to MCF-7, HeLa and DU145 cancer cell lines with IC50 values of 14.24, 7.82 and 22.10 μg mL, respectively. 4-Methoxycinnamyl alcohol was isolated from Foeniculum vulgare. 4-Methoxycinnamyl alcohol did not show apoptotic effects but showed necrosis after 48 h in a 10 μg mL DNA fragmentation study.
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Eupatolide
TN40386750-25-0
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast cancer cells.
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Taraxasterol
Taraxasterin
T37701059-14-9
Taraxasterol (Taraxasterin) is compound with anti-inflammatory activity.
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Paederosidic acid methyl ester
T3S0870122413-01-8
Paederosidic acid methyl ester has antinociception, is possibly related to the pathway of NO-cGMP-ATP sensitive K(+) channels.
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Chamigrenal
T3P285519912-84-6
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor antagonistic activity and the IC(50)
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Rotenone
Rotocide, Rotenon, Paraderil, Dactinol, Barbasco
T297083-79-4
Rotenone (Rotocide) is a natural product and a botanical insecticide. Rotenone is a mitochondrial electron transport complex I inhibitor that promotes the production of reactive oxygen species in mitochondria and induces apoptosis.
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TargetMol | Citations Cited
Gordonoside J
T1260881293918-32-7
Gordonoside J, a compound isolated from the stem of Chrysanthemum officinale, inhibits LPS-induced nitric oxide production in rat polymorphonuclear leukocytes (PMNS).
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4-6 weeks
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Maytansinol
Ansamitocin P-0
T1601657103-68-1
Maytansinol (Ansamitocin P-0) inhibits microtubule assembly and causes microtubule disassembly in vitro.
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Docosahexaenoic Acid
DHA, Cervonic acid
T53696217-54-5
Docosahexaenoic Acid (DHA) is an essential omega-3 fatty acid prevalent in the brain and retina.
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5-Aminosalicylic Acid
Mesalazine, Mesalamine, 5-ASA
T064689-57-6
5-Aminosalicylic Acid (5-ASA) is an anti-inflammatory agent, structurally related to the SALICYLATES, which is active in INFLAMMATORY BOWEL DISEASE. It is considered to be the active moiety of SULPHASALAZINE.
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Ionomycin
T728556092-81-0
Ionomycin is an calcium ionophore and an antibiotic that binds calcium ions (Ca2+). It is produced by the bacterium Streptomyces conglobatus.It is used in research to raise the intracellular calcium level (Ca2+) and as a research tool to understand Ca2+ transport across biological membranes. Ionomycin promotes apoptosis and induces the activation of protein kinase C (PKC).
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7-10 days
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Glycochenodeoxycholic Acid
Glycine chenodeoxycholate, Chenodeoxycholylglycine, GCDCA, Glycochenodeoxycholate, Lithocholylglycine
T4588640-79-9
Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
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Hellebrigenol
TN1729508-79-2
Hellebrigenol is a butadienolide extracted from the venom of the Vietnamese toad (Bufo vulgaris) with antitumor activity.
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7-10 days
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6-diazo-5-oxo-l-nor-leucine
L-6-Diazo-5-oxonorleucine, DON, Diazooxonorleucine
T8373157-03-9
6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) is a glutaminase antagonist (Ki: 6 μM) and an antineoplastic antibiotic produced by an unidentified Streptomyces species from Peruvian soil.
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