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nd646

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ND-646
TQ02431434639-57-2
ND-646 is an orally bioavailable and allosteric inhibitor of the ACC enzymes ACC1 and ACC2, with IC50 values of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.
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CRBN ligand-646
T216927
CRBN ligand-646 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit cereblon protein. It can be linked to a target protein ligand via a linker to form a PROTAC.
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