mek-in-4

MEK-IN-4 is a MEK inhibitor utilized in the study of inflammatory diseases and cancer.

1. Nardosinone has inhibitory effect on Ang II-induced hypertrophy in H9c2 cells, might be mediated by targeting PI3K Akt and MEK ERK signaling pathways. 2. Nardosinone could protect against the neuronal injury exposed to OGD, which may be relevant to the

CML-IN-1, also known as compound 7 and compound 4, is a potent anticancer agent that demonstrates a strong induced-apoptosis effect in the human chronic myeloid leukemia (CML) cell line K562. It diminishes protein phosphorylation within the PI3K Akt signaling pathway to exert its effects and suppresses cell proliferation through the inhibition of the MEK ERK signaling pathway in colorectal cancer [1] [2].