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(12)
By Target- Drug-Linker Conjugates for ADC
- Microtubule Associated(2)
- ADC Antibody(1)
- ADC Linker(1)
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Results for "
mc-mmae
" in TargetMol Product Catalog- Inhibitors & Agonists17
- Inhibitory Antibodies1
- PROTAC Products3
Mc-MMAE
Maleimidocaproyl-monomethylauristatin E
T18312863971-24-8
Mc-MMAE (Maleimidocaproyl-monomethylauristatin E) is a drug-linker conjugate for ADC. Mc-MMAE is a maleimidocaproyl-conjugated monomethyl auristatin E, which is a potent tubulin inhibitor.
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Mc-Val-Cit-PAB-Cl 
T183211639351-92-0
Mc-Val-Cit-PAB-Cl, a cleavable ADC linker, is utilized in the conjugation of MMAE and antibodies to produce compounds such as antibody-MC-vc-MMAE (e.g., anti-CD22-MC-VC-PABC-MMAE), which demonstrate cytotoxicity with IC50s of 3.3 and 0.95 nM against BJAB and WSU cell lines, respectively.
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VCMMAE
mc-vc-PAB-MMAE
T4232646502-53-6
VCMMAE (mc-vc-PAB-MMAE) is a drug-linker conjugate for ADC with potent antitumor activity.
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